Find hotels in Santa Cruz from CA $31

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Compare 231 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
9.2 out of 10, Wonderful, (226)
"It was OK stay. The staff didn't speak English very well though"
The price is CA $101
CA $101 total
includes taxes & fees
Apr 4 - Apr 5
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Swissôtel Santa Cruz De La Sierra

4.5 star property
9.2 out of 10, Wonderful, (75)
"Beautiful hotel"
The price is CA $184
CA $184 total
includes taxes & fees
Apr 15 - Apr 16
Swissôtel Santa Cruz De La Sierra

Premium Suites Deluxe Aparthotel Equipetrol

3.5 star property
9.0 out of 10, Wonderful, (69)
"Very clean! "
The price is CA $76
CA $76 total
includes taxes & fees
Apr 1 - Apr 2
Premium Suites Deluxe Aparthotel Equipetrol

Novotel Santa Cruz De La Sierra

5.0 star property
9.2 out of 10, Wonderful, (87)
"Nice hotel, modern, with pool, good restaurant. Would stay here again without no doubt. "
The price is CA $128
CA $128 total
includes taxes & fees
Apr 16 - Apr 17
Novotel Santa Cruz De La Sierra

Camino Real Hotel

4.5 star property
8.8 out of 10, Excellent, (377)
"Superb Hotel. Lovely staff Pool area great. Close to everything in a good area. "
The price is CA $161
CA $161 total
includes taxes & fees
Apr 4 - Apr 5
Camino Real Hotel

Hotel G

3.5 star property
7.8 out of 10, Good, (103)
"excelente ubicación, muy cómodo el lugar."
The price is CA $60
CA $60 total
includes taxes & fees
Apr 4 - Apr 5
Hotel G

Sun Hotel

3.5 star property
8.2 out of 10, Very good, (284)
"Super easy check in, most of the details are handled by Expedia. It’s a great place to relax before an early morning flight out of VVI. Clean, comfortable and everything you need. "
The price is CA $155
CA $155 total
includes taxes & fees
Apr 1 - Apr 2
Sun Hotel

Apart Hotel Premium Suites Santa Cruz

3.5 star property
8.6 out of 10, Excellent, (85)
"Good location, spacious apartment, good stay overall"
The price is CA $43
CA $43 total
includes taxes & fees
Apr 1 - Apr 2
Apart Hotel Premium Suites Santa Cruz

Hotel Maywa

4.0 star property
9.2 out of 10, Wonderful, (5)
"Personal atento, buen desayuno continental y habitaciones amplias y modernas "
The price is CA $63
CA $63 total
includes taxes & fees
Apr 1 - Apr 2
Hotel Maywa

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
9.0 out of 10, Wonderful, (186)
"Everything was amazing! Great staff and amazing service! "
The price is CA $160
CA $160 total
includes taxes & fees
Apr 25 - Apr 26
Marriott Santa Cruz de la Sierra Hotel

TRYP by Wyndham Santa Cruz

4.0 star property
9.4 out of 10, Exceptional, (111)
"Nice stay with good service "
The price is CA $140
CA $140 total
includes taxes & fees
Apr 1 - Apr 2
TRYP by Wyndham Santa Cruz

Hotel Cortez

3.5 star property
9.0 out of 10, Wonderful, (103)
"Excellent hotel. Nice pool and sauna and small gym - excellent for Bolivia. Friendly staff and decent breakfast. Only gripe is the coffee machine outside the breakfast restaurant: it isn’t free. This is my second stay there in 2 weeks and they had no indication of that the first time. I saw the second time they put a sign saying it was 20bol.. they only charged me 15bol the week prior.. minor detail.. My go to hotel when I arrive in Santa Cruz."
The price is CA $170
CA $170 total
includes taxes & fees
Apr 7 - Apr 8
Hotel Cortez

Hotel LP Santa Cruz Centro

3.0 star property
7.8 out of 10, Good, (277)
"Clean, friendly staff"
The price is CA $75
CA $83 total
includes taxes & fees
Apr 3 - Apr 4
Hotel LP Santa Cruz Centro

Hotel Arenal

3.5 star property
7.4 out of 10, Good, (56)
"Rooms spacious. Service excellent. "
The price is CA $76
CA $76 total
includes taxes & fees
Apr 9 - Apr 10
Hotel Arenal

Lido Hotel

3.0 star property
8.6 out of 10, Excellent, (8)
"I really liked the Lido hotel and the people running it. They were very kind and accommodating. And I wish them the best of everything."
The price is CA $65
CA $65 total
includes taxes & fees
Apr 7 - Apr 8
Lido Hotel

Terranova Suites

3.5 star property
8.0 out of 10, Very good, (89)
"The pictures of the property have to be from a decade ago. This place it is dirty and in poor shape. "
The price is CA $75
CA $75 total
includes taxes & fees
Apr 14 - Apr 15
Terranova Suites

Alfonsina Hotel Boutique by Inboccaluppo

3.5 star property
9.6 out of 10, Exceptional, (32)
"Love it. Will stay again!!"
The price is CA $148
CA $148 total
includes taxes & fees
Apr 14 - Apr 15
Alfonsina Hotel Boutique by Inboccaluppo

Chairú Eco Hotel

3.5 star property
9.4 out of 10, Exceptional, (33)
"Nice and clean hotel "
The price is CA $67
CA $67 total
includes taxes & fees
Apr 3 - Apr 4
Chairú Eco Hotel

Hotel Las Américas

3.0 star property
The price is CA $73
CA $73 total
includes taxes & fees
Apr 1 - Apr 2
Hotel Las Américas

Ibis Santa Cruz DE LA Sierra

3.0 star property
9.6 out of 10, Exceptional, (41)
"Predictable, good vibe. Very good bed."
The price is CA $108
CA $108 total
includes taxes & fees
Apr 16 - Apr 17
Ibis Santa Cruz DE LA Sierra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Santa Cruz awaits: its cafes, zoo, soccer, and more!

San Lorenzo Cathedral which includes a garden

Find out more about Santa Cruz

Find out more about Santa Cruz

Frequently asked questions

What's the best place for a stay in Santa Cruz?

Ibis Santa Cruz DE LA Sierra is a favorite with Expedia customers. This hotel offers a restaurant and free parking. Reviews from our site also recommend Alfonsina Hotel Boutique by Inboccaluppo and Chairú Eco Hotel as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.

What's the top vacation rental that Santa Cruz has to offer?

Casa Vida: Visitors give good reviews to this Santa Cruz vacation home rental, which is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. Some other homes for rent in Santa Cruz include Mi casa su casa, moderna y chic. and Jose Luis Noya. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

To find more details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.

What's the best budget-friendly accommodation in Santa Cruz?

Based on our traveler reviews, Hostal Killa is a top choice for a less expensive stay. Other choices for your budget-friendly stay include residencial francia - Hostel and Urubo Suite - Hostel. View all budget hotels in Santa Cruz.

What's the best accommodation for a family trip to Santa Cruz?

Marriott Santa Cruz de la Sierra Hotel is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices for your stay with the kids include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Novotel Santa Cruz De La Sierra. Attractions like Santa Cruz Zoo and Play Land Amusement Park are also fun for kids of all ages. Find more child-friendly accommodations in Santa Cruz.

What's the best place to stay for a romantic vacation to Santa Cruz?

Buganvillas Hotel Suites & Spa is a favorite 4-star hotel for couples, and features in-room massages and rainfall showerheads. See all romantic hotels in Santa Cruz.

What is the top LGBTQ-friendly accommodation in Santa Cruz?

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santa Cruz.

What's the best pet-friendly hotel in Santa Cruz?

Hotel G is a top hotel for people traveling with their pets, and offers a coffee shop and free WiFi for its human guests. Other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.

Where is the best place to stay close to Plaza 24 de Septiembre?

Adjacent to Plaza 24 de Septiembre, Nomad Hostel is one of the top choices for your stay based on our traveler data, and this property offers a restaurant and a bar. Other good options close by include Senses Centro and Cosmopolitano Hotel Boutique.

What about the best place to stay near Ventura Mall?

One of the top choices for your stay is Camino Real Hotel, located next to Ventura Mall, and this 4-star hotel offers 2 bars and a restaurant. Los Tajibos Hotel And Convention Center and Marriott Santa Cruz de la Sierra Hotel are two other good choices in the immediate area.

What's the best luxury accommodation in Santa Cruz?

Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Novotel Santa Cruz De La Sierra and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your vacation. Find more luxury hotels in Santa Cruz.

What's the best boutique accommodation in Santa Cruz?

Senses Boutique Hotel is a favorite 3.5-star hotel with our travelers looking for a stylish accommodation, featuring 52 guestrooms, 3 restaurants, and a bar.

What are some accommodations with pools in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top hotel with 2 outdoor pools, a children's pool, and 2 restaurants. A couple of other options that offer an onsite pool include Sun Hotel and Buganvillas Hotel Suites & Spa. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Marriott Santa Cruz de la Sierra Hotel is a top luxury spa hotel featuring a rooftop terrace, a fitness center, tennis courts, and a bar. Spend an afternoon at Hotel Spa where you’ll find massage treatments. Other popular spa hotels in Santa Cruz include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.

What's the best hotel for staying near Viru Viru International Airport (VVI)?

Sun Hotel is a popular 3.5-star hotel featuring free breakfast and a restaurant. It's located a short 1.3 mi (2.1 km) from Viru Viru Intl. Airport.

How is it to stay in Santa Cruz?

Visitors to Santa Cruz are sure to enjoy the shopping. Tourists can also enjoy the city's cafes, zoo, and cathedral. In Santa Cruz, there are 225 hotels and other accommodations to choose from. Find out more about Santa Cruz.

What should I do while I'm visiting Santa Cruz?

Cultural venues include Cine Center, Ethno-folkloric Museum, and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre, and Blacutt Square might be worth a visit. Natural beauty is on display at Guembe Biocenter, Arenal Park, and Lomas de Arena Regional Park. Check out what more to see and do in Expedia's Santa Cruz guide.

How should I get around Santa Cruz?

To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.

What's the weather like in Santa Cruz?

The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.