
Santa Cruz Vacation Packages
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Your Santa Cruz Vacation
With one of our vacation packages to Santa Cruz, you'll find countless opportunities for adventure and relaxation. There's so much to experience, including its beaches and lively atmosphere. If taking in sights is part of the program during your trip to Santa Cruz, check out major attractions like Plaza 24 de Septiembre, Guembe Biocenter and Ventura Mall. Whoever you're heading away with and whatever the size of your budget, your dream Santa Cruz vacation is just clicks away with Expedia.
Top Santa Cruz Vacation Deals

Hotel LP Equipetrol
Reviewed on Feb. 21, 2025

Swissôtel Santa Cruz De La Sierra
Reviewed on Feb. 8, 2025


Santa Cruz Hotel Deals

Reviewed on Mar. 25, 2025

Reviewed on Mar. 30, 2025

Reviewed on Mar. 14, 2025
Frequently asked questions
Discover the most popular places to visit in Santa Cruz

Plaza 24 de Septiembre
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
Ventura Mall
During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area.
Guembe Biocenter
Explore the great outdoors at Guembe Biocenter, a lovely green space in Colinas del Urubo. While in the area, you can find time to visit its shops.
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