Charleston Vacation Rentals

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Vacation Rentals in Charleston

Serenity South -- Gardens, River-Views, and Refreshing Space

10.0 out of 10, Exceptional, (128)
"We had a wonderful time at Serenity South! The house is quiet and very clean, in walking distance of fantastic shops and fun places to eat. We look forward to returning next year!"
The price is CA $215
CA $351 total
includes taxes & fees
Mar 30 - Mar 31
Serenity South -- Gardens, River-Views, and Refreshing Space

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

8.8 out of 10, Excellent, (27)
"Amazing property that we simply didn't stay long enough to enjoy in its completeness. Billiards and Putt-Putt on entry, so attractive that we started playing before we even unpacked! I'm very artsy interior, and lots of room and outdoor fire pit, multiple decks, and an in-ground pool. The home is even on the grounds, an event venue. Probably a wonderful combination for them! Would enjoy returning, but for a longer stay will you could enjoy all with the property had to offer! Highly recommend it"
The price is CA $215
CA $334 total
includes taxes & fees
Apr 7 - Apr 8
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Peaceful secluded cabin located near Horseshoe Lake

10.0 out of 10, Exceptional, (3)
"This is a nice to little spot for anyone or a couple looking to just getaway for a night or a weekend. It’s nestled in the middle of the woods with no one around you for what seems like miles. Very quiet place and had everything we needed for our stay. Would definitely stay here again!"
The price is CA $193
CA $279 total
includes taxes & fees
Mar 30 - Mar 31
Peaceful secluded cabin located near Horseshoe Lake

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

The price is CA $428
CA $677 total
includes taxes & fees
Apr 7 - Apr 8
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Cozy cabins on beautiful Horseshoe Lake

9.8 out of 10, Exceptional, (28)
"Quiet place to stay. Comfortable bed. Wish we could have stayed longer but will definitely be back. Nice to actually have a good cup of coffee without taking your own personal coffee pot. "
The price is CA $165
CA $193 total
includes taxes & fees
Mar 30 - Mar 31
Cozy cabins on beautiful Horseshoe Lake

Welcome campers, hikers, fishermen, girls' weekend wine getaways!!

2.0 star property
10.0 out of 10, Exceptional, (7)
"This place is just what we needed for our snow goose hunting camp! Place was clean and tidy and even had a pool table that made for hours of fun! Host went above and beyond to be helpful and was excellent with communication and was even kind enough to bring us some snow goose summer sausage (which was delicious)! I wouldn't hesitate to stay here again and would recommend it to anyone!!!"
The price is CA $286
CA $353 total
includes taxes & fees
Mar 31 - Apr 1
Welcome campers, hikers, fishermen, girls' weekend wine getaways!!

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

9.8 out of 10, Exceptional, (33)
"This was a virtual retreat for me. I stayed 4 nights very comfortably in a location that worked well for getting around Cape Girardeau. The neighbors were very considerate of my quiet time! The bed was very comfortable, and the space was inviting."
The price is CA $130
CA $212 total
includes taxes & fees
Apr 7 - Apr 8
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi

10.0 out of 10, Exceptional, (5)
"A large and comfortable house with cool historical details and just about everything you need to have a great, easy, smooth-running vacation. Great location for downtown exploring."
Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi

Upscale & Quiet Paducah Retreat on 15 Acres!

9.6 out of 10, Exceptional, (26)
"What a beautiful house and location . Everything was perfect . Could not have asked for anything else ."
Upscale & Quiet Paducah Retreat on 15 Acres!

Quaint, Beautiful Home next to SEMO and Hospital

9.8 out of 10, Exceptional, (34)
"The home had everything we needed for a relaxing weekend! Owner responded promptly and everything was as it was listed!"
Quaint, Beautiful Home next to SEMO and Hospital

Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.

7.8 out of 10, Good, (8)
"We stayed here with my cousins family while our daughters were playing at Sportplex. Nice and clean property. Host was easy to communicate with. Would stay here again when in this area. "
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.

Little Blue Cottage on Spanish

8.6 out of 10, Excellent, (39)
"Very easy process and a great location for a convenient stay downtown "
The price is CA $129
CA $157 total
includes taxes & fees
Apr 1 - Apr 2
Little Blue Cottage on Spanish

Loft Apartment Across From Semo University Houch Field House. Walk To Events

10.0 out of 10, Exceptional, (81)
"We came to town for an event on SEMO campus, and this little place was the perfect spot for our group. Would recommend, would stay again!"
The price is CA $215
CA $260 total
includes taxes & fees
Apr 6 - Apr 7
Loft Apartment Across From Semo University Houch Field House. Walk To Events

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

10.0 out of 10, Exceptional, (212)
"There couldn’t be a better location for going out on the riverfront in Cape Girardeau. It is well set up with beautiful furniture and all the kitchen supplies you would need. Highly recommend. "
Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

10.0 out of 10, Exceptional, (164)
"The Red House is in a quiet area and was well stocked with any and everything you might need. The host even provided fresh eggs and muffins for breakfast!!! If we are ever back in the area we will stay here again."
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

"Brickyard" Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau

10.0 out of 10, Exceptional, (13)
"Chip was fantastic and went above and beyond to get us acquainted with the property! Fantastic weekend in a beautiful home with family and friends!"
"Brickyard" Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau

The Rested Duck Mallard Room

9.0 out of 10, Wonderful, (20)
"Excellent "
The price is CA $165
CA $205 total
includes taxes & fees
Mar 30 - Mar 31
The Rested Duck Mallard Room

River's Dawn - Modernized Historic Home - River Views - King Bed - Fast Wifi

10.0 out of 10, Exceptional, (3)
"Was a great location. About a 5 minute walk to downtown Cape. Was perfect for our weekend festivities "
River's Dawn - Modernized Historic Home - River Views - King Bed - Fast Wifi

Charming Home just minutes from Interstate and Mall

10.0 out of 10, Exceptional, (13)
"Quaint house that makes great use of the space. Everything is modern and clean and well organized. A"
The price is CA $157
CA $269 total
includes taxes & fees
Mar 31 - Apr 1
Charming Home just minutes from Interstate and Mall

River Town Retreat near SEMO

9.0 out of 10, Wonderful, (2)
"Very nice place only downsize albeit cute is the claw foot tub with make shift shower, The unit worked very well for what we were looking for near SEMO campus"
The price is CA $131
CA $351 total
includes taxes & fees
Mar 31 - Apr 1
River Town Retreat near SEMO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other types of properties in Charleston you may be interested in

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (548)
"The carpet in the room needs to be vacuumed."
The price is CA $93
CA $103 total
includes taxes & fees
Mar 30 - Mar 31
Super 8 by Wyndham Charleston/Sikeston East MO

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (374)
"Staff were very friendly. Room was spacious and well designed."
The price is CA $108
CA $120 total
includes taxes & fees
Apr 20 - Apr 21
Quality Inn Charleston - Sikeston

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (95)
"Comfortable bed, easy access to room"
The price is CA $91
CA $101 total
includes taxes & fees
Mar 30 - Mar 31
Eagle Inn Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Can I find a vacation rental in Charleston?

Yes, we have vacation rentals close to the most popular sights in Charleston, or you can go with a secluded option if you want a relaxing place to stay. Our travelers say Charleston has a good selection of restaurants. Make sure you have time to check out the entertainment choices and theaters during your trip.

What are some of the best vacation rentals that Charleston has to offer?

Serenity South -- Gardens, River-Views, and Refreshing Space: Visitors like this Charleston vacation home rental. It is located on a river and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games.

What can I see and do in Charleston?

Mississippi River and Ohio River are a couple of lovely local spots to get outside and enjoy nature. Columbus-Belmont State Park and Mound City National Cemetery are a couple of places you'll find in the larger area.

What are vacation rentals like in Charleston?

Vacation rentals are private accommodations you can book for a few days or a quick weekend in Charleston. Vacation rentals feature extras like WiFi and washers and dryers so you'll feel just like you're at home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from shared hotel elevators and bustling concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental a great choice for family trips.