Find hotels in Charleston, MO from CA $86

Quality Inn Charleston - Sikeston is a favorite with Expedia customers. This hotel offers free breakfast and free parking. Another favorite option for your stay based on traveler reviews is Super 8 by Wyndham Charleston/Sikeston East MO. See all available top hotels, or vacation rentals in Charleston.

Serenity South -- Gardens, River-Views, and Refreshing Space: Visitors like this Charleston vacation home rental. It is located on a river and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Charleston.

Yes! You'll find that most room reservations are fully refundable if cancelled before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Charleston.

To find more details about changing or cancelling your trip to Charleston, click here.

Based on reviews, Quality Inn Charleston I-57 is a popular hotel for our travelers who want a more economical choice, and features free buffet breakfast and free WiFi. Another top option for your budget-friendly stay is Eagle Inn Charleston. View all budget hotels in Charleston.

Quality Inn Charleston - Sikeston is a top hotel for people traveling with their pets, and offers free WiFi for its human guests. Two other good options for you and your pet's trip include Super 8 by Wyndham Charleston/Sikeston East MO and Eagle Inn Charleston. See more pet-friendly hotel accommodations in Charleston.

Best Western Plus Sikeston: Features free full breakfast, a pool, and free parking. Pear Tree Inn Sikeston and Drury Inn & Suites Sikeston, MO are a couple of other choices with an onsite pool. View all hotels with pools in Charleston.

Eagle Inn Charleston is a highly recommended spa hotel with a health club.

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

Visitors to Charleston are sure to enjoy the restaurants. Tourists can also enjoy the city's entertainment choices, theaters, and churches. In Charleston, there are 3 hotels and other accommodations to choose from. Find out more about Charleston.

The picturesque setting of Mississippi River and Ohio River exemplify the area's natural beauty. You'll also find Columbus-Belmont State Park and Mound City National Cemetery in the area. Check out what more to see and do in Expedia's Charleston guide.

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Charleston is 59 inches.