2 Stars Hotels in Southeast Missouri, Missouri from CA $80
Check availability on Southeast Missouri 2 Star Hotels
Top Southeast Missouri 2 Star Hotels

Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MO

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston

The Farmstead Hotel
The Farmstead Hotel
Explore similar 3-star hotels

The Riverview
Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Sam A. Baker State Park to K Bridge Recreation Area.

Find out more about Southeast Missouri
Find out more about Southeast Missouri
Want to get out of town on the cheap? Thanks to the low rates and great discounts at the top 2 Stars hotels in Southeast Missouri, Southeast Missouri you can sneak away on the trip of your dreams with plenty of cash to spare. In addition to the friendly staff and well-maintained surroundings, you’ll find comfortable rooms, complimentary bath products, and quiet sleeping areas, so you can kick back with all the basic conveniences after a long day. Plus, these properties are perfect, if you need a jumping-off point for exploring the local attractions.
Several of the best hotels with 2 Stars in Southeast Missouri are situated just a stone’s throw from both public transportation and the city’s main freeways. Use the travel tools at Expedia.ca to search for options near your favorite neighborhood, find a cheap deal, and book your room. You won’t believe how inexpensive your next vacation can be when you settle in at a top two star hotel in Southeast Missouri.
Recent Reviews in Southeast Missouri
Recent Reviews in Southeast Missouri

Motel 6 Poplar Bluff, MO
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Southeast Missouri Hotels by Star Rating
Hotels in Southeast Missouri Neighborhoods
Hotels near Popular Southeast Missouri Attractions
- Hotels near Mark Twain National Forest
- Hotels near Elephant Rocks State Park
- Hotels near Johnson's Shut-ins State Park
- Hotels near Current River
- Hotels near Ozark National Scenic Riverways
- Hotels near Southeast Missouri State University
- Hotels near Echo Bluff State Park
- Hotels near Lake Wappapello
- Hotels near Isle Casino Cape Girardeau
- Hotels near Big Spring
- Hotels near Current River State Park
- Hotels near Century Casino Caruthersville
- Hotels near Alley Spring & Mill
- Hotels near Clearwater Lake
- Hotels near Rocky Falls
- Hotels near Taum Sauk Mountain State Park
- Hotels near K Bridge Recreation Area
- Hotels near Bonne Terre Mine
- Hotels near Sainte Genevieve Winery
- Hotels near Akers Ferry
More Hotel Options in Southeast Missouri
- Adults Only Resorts & Hotels in Southeast Missouri
- Business Hotels in Southeast Missouri
- Casino Hotels in Southeast Missouri
- Cheap Hotels in Southeast Missouri
- Family Hotels in Southeast Missouri
- Golf Hotels in Southeast Missouri
- Historic Hotels in Southeast Missouri
- Hotel Wedding Venues in Southeast Missouri
- Hotels & Resorts for Couples in Southeast Missouri
- Hotels with Balconies in Southeast Missouri
- Hotels with Bar in Southeast Missouri
- Hotels with Childcare in Southeast Missouri
- Hotels with Free Breakfast in Southeast Missouri
- Hotels with Free Parking in Southeast Missouri
- Hotels with Hot Tubs in Southeast Missouri
- Hotels with Kitchenettes in Southeast Missouri
- Hotels with Tennis Courts in Southeast Missouri
- Hotels with Waterslides in Southeast Missouri
- Hotels with Wifi in Southeast Missouri
- Hotels with a Pool in Southeast Missouri
- Hotels with an Indoor Pool in Southeast Missouri
- Hotels with smoking rooms in Southeast Missouri
- Lake Hotels in Southeast Missouri
- Luxury Hotels in Southeast Missouri
- Mountain Hotels in Southeast Missouri
- Pet-friendly Hotels in Southeast Missouri
- Romantic Hotels in Southeast Missouri
- Shopping Hotels in Southeast Missouri
- Ski Hotels in Southeast Missouri
- Spa Hotels in Southeast Missouri
- Winery Hotels in Southeast Missouri
More Accommodation Types in Southeast Missouri
- Vacation Homes in Southeast Missouri
- Cabin Rentals in Southeast Missouri
- Cottages in Southeast Missouri
- Apartments in Southeast Missouri
- Motels in Southeast Missouri
- Farmstay in Southeast Missouri
- RV Parks in Southeast Missouri
- Condo Rentals in Southeast Missouri
- Lodges in Southeast Missouri
- Aparthotels in Southeast Missouri
- B&B in Southeast Missouri
- Villas in Southeast Missouri
Explore more hotels
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Pear Tree Inn Cape Girardeau West
- Drury Inn & Suites Cape Girardeau
- Best Western Plus Sikeston
- Hampton Inn Sikeston
- Drury Inn & Suites Sikeston, MO
- Candlewood Suites Cape Girardeau by IHG
- Drury Inn & Suites Jackson MO
- Quality Inn
- Comfort Inn Festus - St Louis South
- Drury Inn & Suites Hayti Caruthersville
- Holiday Inn Express & Suites Perryville by IHG
- Courtyard by Marriott Cape Girardeau Downtown
- Tru By Hilton Cape Girardeau
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Super 8 by Wyndham Farmington
- Super 8 by Wyndham Perryville
- Days Inn and Suites by Wyndham Sikeston
- Holiday Inn Poplar Bluff by IHG