Wykoff Vacation Rentals

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Check prices for these dates

Tonight
Apr 18 - Apr 19
Tomorrow
Apr 19 - Apr 20
This weekend
Apr 18 - Apr 20
Next weekend
Apr 25 - Apr 27

Vacation Rentals in Wykoff

The Berkman
Terrace/patio

The Berkman

3.0 star property
9.6 out of 10, Exceptional, (283)
"Love the berkman. We stay here at the request of my son every time he has an appt at the mayo. He loves the golf simulator! It's a beautiful place. Highly recommended "
The price is CA $147
CA $170 total
includes taxes & fees
May 16 - May 17
The Berkman
Heritage hideaway-Secluded Log Cabin
2 bedrooms, travel crib, free WiFi, bed sheets

Heritage hideaway-Secluded Log Cabin

10.0 out of 10, Exceptional, (365)
"We had a very lovely weekend stay at this cabin. It was very easy to access many different state parks from the area and the property itself was very beautiful. "
Heritage hideaway-Secluded Log Cabin
Root River Valley Cabin ~ Lanesboro, MN
Exterior detail

Root River Valley Cabin ~ Lanesboro, MN

10.0 out of 10, Exceptional, (300)
"We enjoyed staying here to fish the beautiful streams of the Driftless area. It was a nice quiet location still close to Lanesboro."
Root River Valley Cabin ~ Lanesboro, MN
Century Cottage-PERFECT for Mayo & downtown visitors!
Outdoor dining

Century Cottage-PERFECT for Mayo & downtown visitors!

10.0 out of 10, Exceptional, (110)
"My wife, daughter, and I had a great stay at the Century Cottage this past weekend. The house is very conveniently located between downtown Rochester and the Rochester Recreation Center. It was less than a mile walk/drive to the recreation center and a short drive to downtown Rochester. Mary was also very responsive to any messages we sent. All questions were answered within minutes. We would definitely stay here again if we're ever back in the Rochester area."
Century Cottage-PERFECT for Mayo & downtown visitors!
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Fridge, microwave, oven, stovetop

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

10.0 out of 10, Exceptional, (75)
"The home had tons of character. Very quiet and comfortable. We had everything we needed. Totally enjoyed our stay. "
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Broadway Plaza, Trademark Collection by Wyndham
Fridge, microwave, oven, stovetop

Broadway Plaza, Trademark Collection by Wyndham

3.0 star property
9.2 out of 10, Wonderful, (150)
"Very good"
Broadway Plaza, Trademark Collection by Wyndham
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
Property grounds

Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.

9.8 out of 10, Exceptional, (43)
"This is a wonderful house - great location, very clean, easy access to Mayo Clinic, shopping and restaurants. We will stay again. "
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
Within walking distance of all the amenities! Bike the trail~ float the river
Exterior

Within walking distance of all the amenities! Bike the trail~ float the river

10.0 out of 10, Exceptional, (11)
"We all talked about how clean and relaxing the home was…very clean, updated, well stocked and awesome location. "
Within walking distance of all the amenities! Bike the trail~ float the river
Fresh space near Mayo Clinic and downtown
Microwave, dishwasher, coffee/tea maker, cookware/dishes/utensils

Fresh space near Mayo Clinic and downtown

9.4 out of 10, Exceptional, (18)
"Very clean property. It was comfortable and cute. The owners were responsive to us and so helpful"
Fresh space near Mayo Clinic and downtown
Delightful family home near parks, nature center, 1.5 m to Mayo Clinic downtown
Miscellaneous

Delightful family home near parks, nature center, 1.5 m to Mayo Clinic downtown

10.0 out of 10, Exceptional, (37)
"Had a surgery at Mayo and family needed a place to stay. Everyone has their own room, plenty of seating for meals and tv. Kitchen is well equipped. Great customer service by the owners."
Delightful family home near parks, nature center, 1.5 m to Mayo Clinic downtown
"Don't Bonk Your Head" Small Living
Fridge, microwave, oven, stovetop

"Don't Bonk Your Head" Small Living

9.0 out of 10, Wonderful, (6)
"I love that it’s the basement! So cute, quaint and cozy. Thank you Mark and Sara 🤗"
"Don't Bonk Your Head" Small Living
Mayo Discount Available- 2Bedroom Close to Mayo
Fridge, microwave, oven, stovetop

Mayo Discount Available- 2Bedroom Close to Mayo

8.2 out of 10, Very good, (23)
"Very clear and easy check in process. Parking in definitely a pain if you need more than one spot. No parking on the two closest streets. Very easy walk to Mayo Clinic. Very cozy place with vintage furnishings. Only downfall was there was no ice melter in the place to put down. Everything was glare because of a storm. Toilet will keep running until you play with the handle for it to stop. Even with that I would still stay again. "
Mayo Discount Available- 2Bedroom Close to Mayo
Upscale King Suite—Steps from Mayo Clinic Hospital
Fridge, microwave, oven, stovetop

Upscale King Suite—Steps from Mayo Clinic Hospital

9.6 out of 10, Exceptional, (17)
"Convient, clean and accomidating."
Upscale King Suite—Steps from Mayo Clinic Hospital
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Fridge, microwave, oven, stovetop

☆Dee Dee's Den: A Dharma Dwellings Parent Company☆

10.0 out of 10, Exceptional, (31)
"We came to town to visit a family member at Mayo. The home was just as the listing stated. The house is beautiful and has so much room…more than we could even use. There were lots of supplies for us and we had everything we needed for a comfortable stay. We only needed to contact host about adjusting the temperature and he quickly responded and gave us guidance on that. I would absolutely stay here again and suggest it to others as well. Five stars! "
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Magical Nest Hideaway
Exterior

Magical Nest Hideaway

10.0 out of 10, Exceptional, (113)
"Stayed a couple days. Nice location and friendly owners. "
Magical Nest Hideaway
The Hen House Retreat - A Comfortable Place to Roost
Miscellaneous

The Hen House Retreat - A Comfortable Place to Roost

9.6 out of 10, Exceptional, (73)
"Quaint, cozy, clean and thoughtfully stocked. A surprise: a small shop of handmade jewelry."
The price is CA $249
CA $306 total
includes taxes & fees
Apr 20 - Apr 21
The Hen House Retreat - A Comfortable Place to Roost
Cozy house / small town living. Attractions include trout capital of Minnesota
Property grounds

Cozy house / small town living. Attractions include trout capital of Minnesota

5.6 out of 10, (8)
"We came up for the weekend for our fanily reunion . The house is old & smells like an old house, which isn't a bad thing. The house was clean & tidy. We couldn't find the hot tub,but it was all good. We didn't spend much time at the house, except for sleeping & watching tv in the evening. Thank you for a pleasant stay."
The price is CA $173
CA $297 total
includes taxes & fees
Apr 20 - Apr 21
Cozy house / small town living. Attractions include trout capital of Minnesota
"Walden Pond" Adventure Amidst 44 Private Acres
Interior

"Walden Pond" Adventure Amidst 44 Private Acres

10.0 out of 10, Exceptional, (124)
"The Bungalow was just what our family needed, a few days away from the hustle and bustle. Really enjoyed the trails (went for walks at least twice a day) and the loft, for hanging out. Would stay again. "
"Walden Pond" Adventure Amidst 44 Private Acres
Mayo Discount Offered-Family-Friendly 2 Level-Near Mayo
Interior

Mayo Discount Offered-Family-Friendly 2 Level-Near Mayo

8.2 out of 10, Very good, (18)
"It would have been nice to get a heads up about mowing the lawn and having all the grass swept off of the sidewalk so we weren't walking through it and put it into the car or the house. TV remote was not in there The remote that was there did not go to that TV so we could not hook up our computer. The extras were nice. Surprisingly the two air conditioners kept the house cooled off. Not a bad place to stay would consider staying again."
Mayo Discount Offered-Family-Friendly 2 Level-Near Mayo
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Fridge, microwave, oven, stovetop

Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic

10.0 out of 10, Exceptional, (26)
"This cute house was just perfect for our stay. I had 4 days of Mayo testing stress and this home was a nice escape where we could cook, relax and recharge. It was spotless and welcoming. Downstairs bed was comfy, and perfect for a yet healing back after a major surgery. Would definitely stay again. Broc was responsive and kind in all communication. :)"
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other types of properties in Wykoff you may be interested in

Kahler Grand Hotel
Indoor pool

Kahler Grand Hotel

3.0 star property
8.2 out of 10, Very good, (1347)
"Best location for Mayo. "
The price is CA $191
CA $219 total
includes taxes & fees
May 16 - May 17
Kahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic
Serves lunch, dinner, and happy hour

AmericInn by Wyndham Rochester Near Mayo Clinic

3.0 star property
8.0 out of 10, Very good, (815)
"I liked the restaurant and bar attached to hotel!"
The price is CA $106
CA $122 total
includes taxes & fees
May 4 - May 5
AmericInn by Wyndham Rochester Near Mayo Clinic
Med City Inn & Suites - Mayo Clinic Area
Desk, laptop workspace, iron/ironing board, free WiFi

Med City Inn & Suites - Mayo Clinic Area

2.5 star property
8.0 out of 10, Very good, (1006)
"Noisy, windows need replacing. "
The price is CA $111
CA $128 total
includes taxes & fees
Apr 20 - Apr 21
Med City Inn & Suites - Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Can I find a vacation rental in Wykoff?

Yes, we offer vacation rentals close to well known sights in Wykoff, or you can select a more secluded option if you're looking for relaxation. Wykoff is known for its museums.

What are some of the best vacation home rentals in Wykoff?

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.: This vacation home rental outside of Wykoff is located in the city center and has a balcony, a garden, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the books in this rental home to help you unwind.

What’s there to see and do in Wykoff?

Enjoy the area's cultural attractions such as Ed's Museum, or get outdoors into nature at a spot like Forestville Mystery Cave State Park. In the larger area, you’ll find Four Daughters Vineyard & Winery and Deer Creek Speedway.

What’s a vacation rental in Wykoff like?

Vacation rentals are privately owned properties you can book for a few weeks or just a few days in Wykoff. Vacation rentals offer amenities like kitchens and laundry facilities so you'll feel right at home. If you're concerned about a clean environment, a vacation rental can offer a sense of privacy away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental an attractive choice for a family trip or a small group gathering.