Find Spa Hotels in Panama City from CA $171

  • Plan, book, stay with confidence
    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Top Panama City Spa Hotels

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Meeting facility
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
8.8 out of 10, Excellent, (885)
"I will definitely stay here again. The staff went beyond the call of duty to help non spanish speaking customers"
The price is CA $208
CA $229 total
includes taxes & fees
Dec 8 - Dec 9
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Exterior
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
9.6 out of 10, Exceptional, (514)
"Beautiful resort with very helpful and friendly staff. The food was amazing! I’ll definitely be back."
The price is CA $236
CA $260 total
includes taxes & fees
Dec 13 - Dec 14
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Marriott Panama Hotel
Terrace/patio
Marriott Panama Hotel
4.0 star property
9.0 out of 10, Wonderful, (1000)
"Helpful friendly staff, accommodating to most requests. The hotel location seems to be in an industrial area, so only the mall options-which is hugh- is available for entertainment within walking distance."
The price is CA $201
CA $221 total
includes taxes & fees
Dec 21 - Dec 22
Marriott Panama Hotel
Bristol Panama, a Registry Collection Hotel
Couples treatment rooms, steam room, Turkish bath, body treatments
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1001)
"It is a great hotel, with great staff and superb personalized service. Totally recommended!"
The price is CA $237
CA $261 total
includes taxes & fees
Dec 21 - Dec 22
Bristol Panama, a Registry Collection Hotel
W Panama
Marvelous Suite, Suite, 1 King Bed, Non Smoking, City View
W Panama
5.0 star property
8.8 out of 10, Excellent, (1002)
"Lo único que puedo decir es que el baño mejor la ducha tiene moho. Todo lo demás estuvo muy lindo y bueno"
The price is CA $178
CA $195 total
includes taxes & fees
Dec 20 - Dec 21
W Panama
Sofitel Legend Casco Viejo, Panama City
Exterior
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8 out of 10, Exceptional, (337)
"Very clean and the staff was very friendly and helpful always checking to see how they could improve my wonderful experience "
The price is CA $409
CA $450 total
includes taxes & fees
Dec 19 - Dec 20
Sofitel Legend Casco Viejo, Panama City
Sheraton Grand Panama
Outdoor pool, pool umbrellas, sun loungers
Sheraton Grand Panama
4.0 star property
8.4 out of 10, Very good, (816)
"The front desk staff was extremely hepful with suggestions of local tours and experiences. They were also quite thoughtful- sent a birthday cake to my mom's room. They added joy to our overall experience "
The price is CA $191
CA $210 total
includes taxes & fees
Nov 29 - Nov 30
Sheraton Grand Panama
Hilton Panama
Outdoor pool
Hilton Panama
5.0 star property
8.8 out of 10, Excellent, (1003)
"The hotel was modern and well maintained. Staff were friendly and helpful. Loved how central it was and close to everything."
The price is CA $194
CA $214 total
includes taxes & fees
Dec 7 - Dec 8
Hilton Panama
JW Marriott Panama
4 outdoor pools, cabanas (surcharge), pool umbrellas
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1002)
"This hotel did not disappoint. The staff was friendly offering round the clock service. All of the property amenities were excellent, with breathe taking views. If my itinerary wasn’t so busy for my stay, I would have loved to just stay at the hotel longer to relax. I will def be back"
The price is CA $211
CA $232 total
includes taxes & fees
Dec 7 - Dec 8
JW Marriott Panama
Aloft Panama
Exterior
Aloft Panama
3.5 star property
8.6 out of 10, Excellent, (763)
"Beautiful. Great. 10/10. Had a cancelled flight and this was great and I’m a really great area. I’d stay here again for a couple of nights. "
The price is CA $171
CA $188 total
includes taxes & fees
Nov 28 - Nov 29
Aloft Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Panama City
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until December 4 with our Black Friday deals. Stay by December 15, 2025.
Unlock Black Friday deals

Frequently asked questions

Looking to vacation at a spa hotel in Panama City?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers highly recommend Panama City for its array of shops and gourmet restaurants—your day tour starts here. Be sure to enjoy the cafes during your stay. Spa hotels are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping mall, and a rooftop terrace. Enjoy a facial, body scrub, or detox wrap at the onsite spa. Other popular spa hotels in Panama City include Decapolis Hotel Panama City and Las Americas Golden Tower Panama.
How many spa hotels are there in Panama City?
Expedia has 19 spa hotels to choose from in Panama City.
What's there to see and do in Panama City?
Enjoy Panama City with a stop at Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have a little extra time during your trip, you might want to check out Uruguay Street and Multicentro Panama.
What is a Panama City spa hotel?
Spa hotels in Panama City have full on-site spas which offer services like massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.