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Find Hotels by Independent in De Soto from CA $55
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Top De Soto Independent Hotels

Cute Ranch -safe and quiet- 1800 sft living space
Cute Ranch -safe and quiet- 1800 sft living space
9.6 out of 10, Exceptional, (18)
The price is CA $191
CA $454 total
includes taxes & fees
Apr 27 - Apr 28

Postcard Cabins St. Francois
Postcard Cabins St. Francois
10.0 out of 10, Exceptional, (4)
The price is CA $125
CA $186 total
includes taxes & fees
Apr 27 - Apr 28

Carol's Cottage
Carol's Cottage
10.0 out of 10, Exceptional, (1)

Charming small town! Whole house
Charming small town! Whole house
9.6 out of 10, Exceptional, (8)
The price is CA $125
CA $228 total
includes taxes & fees
Apr 28 - Apr 29

Cozy Three bedroom home in Central Farmington
Cozy Three bedroom home in Central Farmington
9.6 out of 10, Exceptional, (21)
The price is CA $166
CA $358 total
includes taxes & fees
Apr 27 - Apr 28

82 Acre Hobby Farm with Lincoln Log Cabin
82 Acre Hobby Farm with Lincoln Log Cabin
10.0 out of 10, Exceptional, (35)
The price is CA $208
CA $387 total
includes taxes & fees
Apr 28 - Apr 29

Newly remodeled house close to downtown and minutes away from golf courses
Newly remodeled house close to downtown and minutes away from golf courses
10.0 out of 10, Exceptional, (14)
The price is CA $136
CA $263 total
includes taxes & fees
Apr 27 - Apr 28

Cabin 1 at the Pallet Factory
Cabin 1 at the Pallet Factory
9.6 out of 10, Exceptional, (28)
The price is CA $55
CA $192 total
includes taxes & fees
May 5 - May 6
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find out more about De Soto
Find out more about De Soto
Independent De Soto Hotel Guide
Some globe-trotters will stay anywhere that offers a cheap deal, but others prefer to book with their favourite chain. Thanks to Expedia.ca’s range of Independent in De Soto, Missouri, you no longer have to choose between the two. Known for their comfortable rooms and friendly staff, each of the best Independent De Soto promises a top quality travel experience.
Recent Reviews in De Soto
Recent Reviews in De Soto

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
5/5 Excellent
"Large shopping area and ease of travel."
A verified traveller stayed at La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Posted 17 hours ago
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Hotels near popular De Soto Attractions
More Accommodation Types in De Soto
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- Super 8 by Wyndham Farmington
- WoodSpring Suites St. Louis Arnold
- Super 8 by Wyndham Bonne Terre
- Quality Inn Farmington
- Postcard Cabins St. Francois
- Hampton Inn Farmington
- Crown Pointe Lodge, BW Signature Collection
- Super 8 by Wyndham Potosi
- Cute Ranch -safe and quiet- 1800 sft living space
- Quality Inn Festus
- Holiday Inn Express & Suites Farmington by IHG
- Cabin 1 at the Pallet Factory
- Treehouse and Hot Tub on 10acres - Pet Friendly!
- Cozy country setting 4 miles from route 66
- Charming 1-bedroom house in nice Imperial with AC. Attn! Traveling Contractors
- Serenity Log Inn -Log out and Log Inn to Serenity
- The Conner House B&B
- Bluebird Meadows with In-ground Pool and Hot Tub! 125 ACRES TO EXPLORE
- Cute town house -3 Queen beds
- Nice big Ranch home - safe & quiet -0.5 acre lot
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