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Find Hotels by Independent in De Soto from CA $67
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Top De Soto Independent Hotels

Cute Ranch -safe and quiet- 1800 sft living space
Cute Ranch -safe and quiet- 1800 sft living space
9.6 out of 10, Exceptional, (18)
The price is CA $208
CA $462 total
includes taxes & fees
Apr 1 - Apr 2

Postcard Cabins St. Francois
Postcard Cabins St. Francois
10.0 out of 10, Exceptional, (3)
The price is CA $129
CA $139 total
includes taxes & fees
Mar 31 - Apr 1

Carol's Cottage
Carol's Cottage

Charming small town! Whole house
Charming small town! Whole house
9.8 out of 10, Exceptional, (7)
The price is CA $129
CA $235 total
includes taxes & fees
Mar 31 - Apr 1

Cozy Three bedroom home in Central Farmington
Cozy Three bedroom home in Central Farmington
9.6 out of 10, Exceptional, (18)
The price is CA $172
CA $374 total
includes taxes & fees
Mar 31 - Apr 1

82 Acre Hobby Farm with Lincoln Log Cabin
82 Acre Hobby Farm with Lincoln Log Cabin
10.0 out of 10, Exceptional, (35)
The price is CA $215
CA $400 total
includes taxes & fees
Mar 31 - Apr 1

Newly remodeled house close to downtown and minutes away from golf courses
Newly remodeled house close to downtown and minutes away from golf courses
10.0 out of 10, Exceptional, (12)
The price is CA $140
CA $268 total
includes taxes & fees
Apr 6 - Apr 7

Cabin 1 at the Pallet Factory
Cabin 1 at the Pallet Factory
9.6 out of 10, Exceptional, (28)
The price is CA $67
CA $210 total
includes taxes & fees
Apr 1 - Apr 2
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Find out more about De Soto
Find out more about De Soto
Independent De Soto Hotel Guide
Some globe-trotters will stay anywhere that offers a cheap deal, but others prefer to book with their favourite chain. Thanks to Expedia.ca’s range of Independent in De Soto, Missouri, you no longer have to choose between the two. Known for their comfortable rooms and friendly staff, each of the best Independent De Soto promises a top quality travel experience.
Recent Reviews in De Soto
Recent Reviews in De Soto

Pear Tree Inn St. Louis Arnold
5/5 Excellent
"A gem hidden away in Arnold, MO."
A verified traveller stayed at Pear Tree Inn St. Louis Arnold
Posted 3 days ago
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Explore a world of travel with Expedia
Hotels near popular De Soto Attractions
More Accommodation Types in De Soto
Explore more hotels
- Comfort Inn Festus - St Louis South
- Super 8 by Wyndham Bonne Terre
- Quality Inn Farmington
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
- Super 8 by Wyndham Farmington
- Cute Ranch -safe and quiet- 1800 sft living space
- Hampton Inn Farmington
- Crown Pointe Lodge, BW Signature Collection
- Quality Inn Festus
- Charming 1-bedroom house in nice Imperial with AC. Attn! Traveling Contractors
- Super 8 by Wyndham Potosi
- Cabin 1 at the Pallet Factory
- Treehouse and Hot Tub on 10acres - Pet Friendly!
- Holiday Inn Express & Suites Farmington by IHG
- Serenity Log Inn -Log out and Log Inn to Serenity
- Lake Haven - Updated Mid Century Cabin Only 35 Mins from St. Louis
- Cozy country setting 4 miles from route 66
- The Conner House B&B
- Cute town house -3 Queen beds
- Couples Retreat with hot tub (cabin2)
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