Santa Clara Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • payments icon
    Better together
    Save up to CA $1,096 when you book a flight and hotel together*
    lob hotels icon
    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon
    Rest easy
    Plan, book, and manage your trip all in one place

Your Santa Clara Vacation

Enjoy amazing adventures when you lock in a vacation package to Santa Clara. Whether you're a history buff, art enthusiast or just a traveler who loves discovering new places, there's something for everyone in this lively city. Every trip to Santa Clara needs a well-planned itinerary. Fill yours with big-name attractions like Farallon Island, La Casa de Lourdes Outdoor Spa and Parroquia Santiago Apóstol de Río Hato. Stop dreaming and start traveling. Explore the many options on Expedia today and put your Santa Clara vacation plans in motion!

Top Santa Clara Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B
Residencia Natural
Central Hotel Panama Casco Viejo
Punta Caracol Acqua Lodge
Las Americas Golden Tower Panama

Ready to book your vacation to Santa Clara?

 

Choose your dates

Santa Clara Hotel Deals

Villa Botero By Casa Mojito B&B
Villa Botero By Casa Mojito B&B
3 out of 5
Calle Central, 5, Rio Hato, Cocle
The price is CA $142 per night from May 15 to May 16
CA $142
CA $142 total
includes taxes & fees
May 15 - May 16
9.6/10 Exceptional! (59 reviews)
"Wonderful little hotel. With only three"

Reviewed on Apr. 21, 2025

Villa Botero By Casa Mojito B&B
Las Sirenas de Santa Clara
Las Sirenas de Santa Clara
3 out of 5
Carretera Interamericana Km.113, Rio Hato, Cocle
10/10 Exceptional! (1 review)
Excelente lugar para Familia - Enfocarse en eso!!
"Todo estuvo perfecto, solo pienso que si deben controlar un poco las personas que se hospedan en las cabañas, ejemplo: todas las cabañas que estábamos eramos familias con niños solo una donde todos eran jóvenes, esa cabaña tenia música y bulla hasta altas horas de la noche y aunque varios de las ..."

Reviewed on May 2, 2017

Las Sirenas de Santa Clara
 Grand Decameron Panama, A Trademark All Inclusive Resort
Grand Decameron Panama, A Trademark All Inclusive Resort
3.5 out of 5
Avenida Principal Farallon. Kilometro 11, Carretera Interamericana - Penonome, Rio Hato, Cocle
Fully refundableReserve now, pay when you stay
The price is CA $253 per night from Apr. 28 to Apr. 29
CA $253
CA $278 total
includes taxes & fees
Apr 28 - Apr 29
7.2/10 Good! (1,000 reviews)
"I had not been to Decameron since 2016 - the property still looks the same a bit aged. The service and quality of food went down a lot. We have many memories of this place when we used to come every year with our kids. It’s dear to my heart but not sure I would recommend it for a first timer in Rio ..."

Reviewed on Apr. 13, 2025

Grand Decameron Panama, A Trademark All Inclusive Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Clara vacation package cost?
You’ll find cheap prices from CA $1,300 on Expedia for your Santa Clara escape. However, factors like the length of stay, hotel choice and season will influence how much your vacation to Santa Clara costs.
What are the cheapest months to go to Santa Clara?
Plan your trip for the off-peak season and you’re likely to get cheap Santa Clara vacation packages. Remember that public holidays and local festivals and events can impact prices, so do some research before you go.
How many days is enough for Santa Clara?
The ideal duration of your Santa Clara vacation depends on what you’d like to do and see. Generally, a handful of days to a week will give you enough time to visit all the leading attractions and explore some hidden treasures along the way.
How to find the best Santa Clara package deals?
Bagging a cheap Santa Clara package deal is a breeze with Expedia. After you’ve entered your destination and preferred dates under our “Packages” tab, set your budget, add a few filters and browse what’s available. You can personalize your search by “Property class,” “Number of bedrooms,” “Traveler experience” and more. Sort the results by “Price: low to high” to discover the most economical Santa Clara package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Santa Clara vacation as a package?
You can enjoy significant savings on your next Santa Clara getaway by booking a tailored vacation package. Click on the “Package” heading, then enter your travel dates and destination to view some great hotel and flight prices. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Santa Clara?
Score incredible bargains by booking your flights ahead of time with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for a spur-of-the-moment Santa Clara vacation.
How to plan a trip to Santa Clara?

  1. Choose when to travel: Check your calendar and get your bags packed. Your favorite time of year and the type of activities available will also help you decide when to vacation in Santa Clara.
  2. Budget wisely: As well as the price of your accommodations, you should factor in other expenses too. These include flights, transportation and food. Also, set aside a little extra for unexpected costs that may come up during your trip to Santa Clara.
  3. Decide your trip length: Consider how long you want to spend discovering Santa Clara. Plan your itinerary so you can get to all the activities and attractions you’re interested in without rushing.
  4. Bundle your flights and hotel: Awesome destination, check. Length of stay, check. All that’s left now is to pick a Santa Clara vacation package that brings all your bookings together.

Discover the most popular places to visit in Santa Clara

What to do in Santa Clara

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.