
Florence Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to CA $1,096 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Your Florence Vacation
With a Florence vacation package, say goodbye to travel planning and hello to an effortless adventure. Every detail of your escape has been taken care of before you go, so you can get on with experiencing this awesome city. If your trip to Florence includes some sightseeing, hit up well-known attractions like Florence Civic Center, Magnolia Mall and Florence National Cemetery. Check out Expedia's wide range of travel options and start organizing your perfect vacation to Florence today.
Florence Hotel Deals

Howard Johnson by Wyndham Florence
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
The price is CA $91 per night from Apr. 27 to Apr. 28
CA $91
CA $102 total
includes taxes & fees
Apr 27 - Apr 28
8.6/10 Excellent! (2,200 reviews)
"So at first I was a little worried about my choice. But once I drove around the property I felt at ease. When I walked in the room I was taken back by how nice and pretty it was inside! At the price it is definitely worth it! Made our trip from Florida a much easier experience!"
Reviewed on Apr. 20, 2025

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from May 18 to May 19
CA $123
CA $138 total
includes taxes & fees
May 18 - May 19
7.8/10 Good! (1,186 reviews)
"Great place to stay"
Reviewed on Apr. 18, 2025

Park Inn by Radisson Florence, SC
1729 Mandeville Road, Florence, SC
Fully refundableReserve now, pay when you stay
The price is CA $137 per night from May 4 to May 5
CA $137
CA $154 total
includes taxes & fees
May 4 - May 5
9/10 Wonderful! (2,038 reviews)
"New modern hotel. Very clean. Conveniently located off highway."
Reviewed on Apr. 20, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
What to do in Florence
Other vacations you might like
- January Vacations and Deals
- February Vacations and Deals
- March Vacations and Deals
- April Vacations and Deals
- May Vacations and Deals
- June Vacations and Deals
- July Vacations and Deals
- August Vacations and Deals
- September Vacations and Deals
- October Vacations and Deals
- November Vacations and Deals
- December Vacations and Deals
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.