Santa Isabel Vacation Packages

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Top Santa Isabel Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Panamonte

Hotel Panamonte

3.5 out of 5
per person
May 31 - Jun. 7
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Panama City (PTY)
9.4/10 Exceptional! (97 reviews)
The staff, including the maid service were excellent. However, whenever the wind blew the windows shook and banged, making it difficult to sleep.

Reviewed on Mar. 24, 2025

Isla Palenque Member of the Cayuga Collection

Isla Palenque Member of the Cayuga Collection

4 out of 5
Save 100% on your flight
per person
May 6 - May 12
found 1 day ago
Roundtrip flight included
Montreal (YUL) to Panama City (PTY)
10/10 Exceptional! (6 reviews)
Absolutely incredible time!

Reviewed on May 7, 2024

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Jun. 1 - Jun. 8
found 1 day ago
Roundtrip flight included
Edmonton (YEG) to Panama City (PTY)
9/10 Wonderful! (863 reviews)
Restaurant is overpriced, zero quality or food proposition and the staff is really bad. It is a pity, since the hotel and the concierge are very nice.

Reviewed on Mar. 27, 2025

The Gray by Wynwood House

The Gray by Wynwood House

2 out of 5
Bella Vista
Save 100% on your flight
per person
Jun. 15 - Jun. 21
found 20 hours ago
Roundtrip non-stop flight included
Montreal (YUL) to Panama City (PTY)
No reviews
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Save 100% on your flight
per person
May 12 - May 19
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
8.6/10 Excellent! (139 reviews)
This is such a cool place! Beautiful surroundings and a unique experience. It is rustic, but a fun adventure. You must climb up and down quite steep stairs to get to the bedroom. Unfortunately, we had lots of rain, so took the water taxi into town and did some exploring. We went to red frog beach. Beautiful! Staff are nice. Food good. Not many vegetarian options, but overall good. We kayaked and snorkeled. Beautiful! I highly recommend.

Reviewed on Mar. 28, 2025

Ready to book your vacation to Santa Isabel?

 

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Santa Isabel Hotel Deals

Private Ocean-Front Cabin with private bathroom on San Blas Island
Private Ocean-Front Cabin with private bathroom on San Blas Island
2 out of 5
Diablo Island, Narganá, Guna Yala
The price is CA $299 per night from Apr. 1 to Apr. 2
CA $299
CA $329 total
includes taxes & fees
Apr 1 - Apr 2
Private Ocean-Front Cabin with private bathroom on San Blas Island
San Blas Paradise Private Cabins on Shipwreck Island - meals included
San Blas Paradise Private Cabins on Shipwreck Island - meals included
2 out of 5
Perro Island, Narganá, Guna Yala
The price is CA $242 per night from Apr. 12 to Apr. 13
CA $242
CA $266 total
includes taxes & fees
Apr 12 - Apr 13
San Blas Paradise Private Cabins on Shipwreck Island - meals included
Private Over the Water Cabin on San Blas Island
Private Over the Water Cabin on San Blas Island
2 out of 5
9.542876, -78.899058, Narganá, San Blas
The price is CA $299 per night from Mar. 31 to Apr. 1
CA $299
CA $329 total
includes taxes & fees
Mar 31 - Apr 1
6.4/10 (5 reviews)
"Communication was good and highly organized. We felt safe and didn’t need to lock up our bags or valuables at all times. Weather was rough (not their fault) so the stay was a challenge with super high winds and rain. The island was covered in trash nearly all the way around. Our cabin doors were ..."

Reviewed on Feb. 16, 2022

Private Over the Water Cabin on San Blas Island
See all 43 properties in Santa Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Frequently asked questions

How much does a Santa Isabel vacation package cost?
You’ll find cheap prices from CA $1,468 on Expedia for your Santa Isabel getaway. However, factors like the season, choice of hotel and length of stay will determine how much your vacation to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
You can generally find lower rates and greater availability in May, August and September. Take a look at our cheap Santa Isabel vacation packages and you could get some great off-season discounts.
How many days is enough for Santa Isabel?
The ideal duration for your Santa Isabel vacation depends on what you’d like to see and do. Typically, a handful of days to a week will give you time to tick off all the major sights and explore some hidden gems along the way.
How to find the best Santa Isabel package deals?
Finding a cheap Santa Isabel package deal is a breeze with Expedia. Once you’ve entered your destination and travel dates under our “Packages” tab, set your maximum budget, add a few filters and see what’s available. You can personalize your search by “Area,” “Amenities,” “Property type” and more. Sort the results by “Price: low to high” to discover the most wallet-friendly Santa Isabel package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book a Santa Isabel vacation as a package?
You can enjoy significant savings on your Santa Isabel break by booking a personalized vacation package. Click on the “Package” heading, then select your travel dates and destination to browse some great airfares and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Santa Isabel?
Enjoy incredible bargains by reserving your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for a spur-of-the-moment Santa Isabel getaway.
How to plan a trip to Santa Isabel?

  1. Choose the perfect time to travel: Your schedule, favorite season and the type of weather you like can all impact your decision on when to travel to Santa Isabel.
  2. Set your budget: Factor in expenses such as transportation, flights and meals when working out how much to set aside for your trip to Santa Isabel. Then, select a property that suits your budget, whether that’s a wallet-friendly option or a lavish getaway.
  3. Decide how long to go for: Now that you’re up to speed on Santa Isabel, you can work out the perfect length of your vacation. Create a draft plan and allocate enough time to cover everything you want to see.
  4. Combine your accommodations and airfare: Once you’ve nailed down your trip dates and duration, book the ideal Santa Isabel vacation package for you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.