Santa Cruz Vacation Packages

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Top Santa Cruz Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Panamonte

Hotel Panamonte

3.5 out of 5
Save 100% on your flight
per person
Apr. 15 - Apr. 22
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
9.4/10 Exceptional! (91 reviews)
Absolutely beautiful and charming old inn. Gorgeous grounds. Excellent dinner on the restaurant. Very helpful staff.

Reviewed on Feb. 7, 2025

Residencia Natural

Residencia Natural

3 out of 5
per person
Apr. 15 - Apr. 22
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
10/10 Exceptional! (6 reviews)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Apr. 15 - Apr. 22
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
9/10 Wonderful! (810 reviews)
Beautiful historic hotel in the middle of Casco Viejo. Perfect location for exploring.

Reviewed on Feb. 20, 2025

The Gray by Wynwood House

The Gray by Wynwood House

2 out of 5
Bella Vista
Save 100% on your flight
per person
May 15 - May 22
found 14 hours ago
Roundtrip flight included
Montreal (YUL) to Panama City (PTY)
No reviews
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Save 100% on your flight
per person
Apr. 15 - Apr. 22
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
8.8/10 Excellent! (136 reviews)
This was the perfect ecolodge on the water! Maria, who owns and manages the lodge, always went over and above for our family to arrange day trips/boat rides to town and provided amazing travel guidance. We needed to charge our phones at reception but it was a small price to pay for a beautiful and unique Panama experience with great rooms and gorgeous views. We ate our breakfasts and lunches on site but preferred the restaurants in town for dinner. Our teens loved it and want to go back! Highly recommend!

Reviewed on Jan. 4, 2025

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Santa Cruz Hotel Deals

Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
3 out of 5
Volcan, Via Cerro Punta, Volcan, Chiriqui
Fully refundableReserve now, pay when you stay
The price is CA $185 per night from Mar. 4 to Mar. 5
CA $185
CA $203 total
includes taxes & fees
Mar 4 - Mar 5
8/10 Very Good! (209 reviews)
"Just awesome"

Reviewed on Feb. 3, 2025

Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
Los Quetzales Ecolodge & Spa
Los Quetzales Ecolodge & Spa
3 out of 5
Guadalupe, Cerro Punta, Chiriqui
Fully refundableReserve now, pay when you stay
The price is CA $125 per night from Mar. 24 to Mar. 25
CA $125
CA $137 total
includes taxes & fees
Mar 24 - Mar 25
8.6/10 Excellent! (24 reviews)
If you look for cool weather in Panama!
"We were there just one night. Got there past 8 pm, hungry and the restaurant was already closed, didn’t get much help from the staff. It took them half an hour to charge my credit card for the cost of the room and we had to drive 20 minutes, back to the city, to find a place to eat. Back at the room ..."

Reviewed on Jan. 13, 2025

Los Quetzales Ecolodge & Spa
Hotel Finca Lerida
Hotel Finca Lerida
3 out of 5
Alto Quiel, Los Naranjos, Chiriqui
The price is CA $313 per night from Mar. 23 to Mar. 24
CA $313
CA $346 total
includes taxes & fees
Mar 23 - Mar 24
8.6/10 Excellent! (175 reviews)
"Best place in Panama. We drove from Panama City eight hours but worth it We loved the national park feel hiked the trails (even to the waterfall) had great food and the best coffee, Ask Roosevelt in the dining room how he got his name. Don’t miss this place"

Reviewed on Feb. 10, 2025

Hotel Finca Lerida
See all 47 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Frequently asked questions

What are the cheapest months to go to Santa Cruz?
If you’re hoping to book a cheap Santa Cruz vacation package, consider traveling in August, September and October. You’re likely to find better prices on airfares and hotels during these months — perfect for a budget-friendly break.
How many days is enough for Santa Cruz?
Typically, a handful of days is enough to check out the main sights during your Santa Cruz vacation. But if you’d like to have more time to relax or go on day tours, consider extending your trip.
How to find the best Santa Cruz package deals?
Use Expedia’s filters to find some terrific Santa Cruz package deals. When you begin your search, simply set your maximum budget and then sort the results by “Price: low to high.” If you want to save, plan your break for midweek, or browse for Santa Cruz package deals in the off-season. Switch up your travel dates and you may score even bigger discounts. As a rule of thumb, it’s usually best to lock in your vacation package as early as possible.
When to book a vacation package to Santa Cruz?
If you have your Santa Cruz vacation dates confirmed, book as early as you can to bag some terrific deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spontaneous adventures? Our last-minute deals are perfect for impromptu escapes.
How to plan a trip to Santa Cruz?

  1. Pick the perfect time to travel: Your schedule, preferred season and the type of weather you like can all influence your decision on when to visit Santa Cruz.
  2. Work out your budget: Ensure you have enough money to pay for everything from transportation and food to flights and experiences. Your accommodations will probably be the largest expense during your trip to Santa Cruz.
  3. Decide how many days away: Start by compiling a list of the activities and attractions you want to experience in Santa Cruz. Then, estimate how long you’ll need at each, as well as any travel time.
  4. Bundle your flights and hotel: Awesome destination, check. Length of stay, check. All that’s left is to pick a Santa Cruz vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.