Panama Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

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    Better together
    Save up to CA $1,096 when you book a flight and hotel together*
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    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy
    Plan, book, and manage your trip all in one place

Top Panama Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield
The Wildwood Hotel
 White House at Grand Central
DoubleTree by Hilton St. Louis Forest Park
Hampton Inn By Hilton St Louis Airport

Ready to book your vacation to Panama?

 

Choose your dates

Panama Hotel Deals

Holiday Inn Express & Suites Litchfield West, an IHG Hotel
Holiday Inn Express & Suites Litchfield West, an IHG Hotel
2.5 out of 5
4 Thunderbird Circle, Litchfield, IL
Fully refundable
The price is CA $166 per night from Apr. 5 to Apr. 6
CA $166
CA $183 total
includes taxes & fees
Apr 5 - Apr 6
9.4/10 Exceptional! (499 reviews)
"Great night. No Loud Children or ill cleaned rooms. Thank you."

Reviewed on Mar. 5, 2025

Holiday Inn Express & Suites Litchfield West, an IHG Hotel
Baymont by Wyndham Litchfield
Baymont by Wyndham Litchfield
2.5 out of 5
1405 W Hudson Dr, Litchfield, IL
Fully refundableReserve now, pay when you stay
The price is CA $142 per night from Mar. 7 to Mar. 8
CA $142
CA $156 total
includes taxes & fees
Mar 7 - Mar 8
8.4/10 Very Good! (989 reviews)
"Good service"

Reviewed on Mar. 2, 2025

Baymont by Wyndham Litchfield
Comfort Inn & Suites Greenville I-70
Comfort Inn & Suites Greenville I-70
2.5 out of 5
2265 S. State Route 127, Greenville, IL
Fully refundableReserve now, pay when you stay
The price is CA $122 per night from Mar. 23 to Mar. 24
CA $122
CA $135 total
includes taxes & fees
Mar 23 - Mar 24
8.4/10 Very Good! (356 reviews)
"Staff was great. There was glass in the pool. My child cut their toe and another cut their foot. Very disappointing. Rooms are basic and need updating."

Reviewed on Mar. 2, 2025

Comfort Inn & Suites Greenville I-70
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Panama vacation package cost?
Offering great value package deals from CA $1,130 on Expedia, you’ll be pleasantly surprised at how much a vacation to Panama costs! Expedia’s packages make travel planning easier and save you more.
What are the cheapest months to go to Panama?
You can typically find reduced prices and better availability in January, February and November. Browse our cheap Panama vacation packages and you could score some great off-season discounts.
How many days is enough for Panama?
The ideal duration of your Panama vacation depends on what you’d like to see and do. Usually, a few days to a week will give you time to tick off all the top attractions and explore some hidden treasures along the way.
How to find the best Panama package deals?
Use Expedia’s filter tool to find some of the best Panama package deals. When you start your search, just set your maximum budget and then sort the results by “Price: low to high.” If you’re looking to save, plan your escape for midweek, or search for Panama package deals in the off-peak season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it’s usually best to book your vacation package well in advance.
Is it cheaper to book a Panama vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging accommodations and flights individually. Better still, you can customize your Panama getaway to fit your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Panama?
If you have your Panama travel dates locked in, book as soon as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to a year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are great for setting off on a whim.
How to plan a trip to Panama?

  1. Pick the perfect time to travel: Your schedule, preferred season and the type of weather you enjoy can all impact your decision on when to go to Panama.
  2. Budget wisely: On top of the cost of your stay, you should consider other expenses too. These include flights, food and transportation. Also, put aside some extra funds for unexpected expenses that may crop up during your trip to Panama.
  3. Decide how long to go away for: Now that you know more about Panama, you can figure out the ideal length of your break. Pull together a rough plan and give yourself enough time to cover everything you want to see.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, flights, hotels and more into a tailored Panama vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.