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Check prices for these dates

Next weekend
Apr 11 - Apr 13
In two weeks
Apr 18 - Apr 20
In one month
May 2 - May 4
In two months
May 30 - Jun 1

Browse Select Los Osos Villas

Diamond Resorts San Luis Bay Inn - Studio
Marina

Diamond Resorts San Luis Bay Inn - Studio

Diamond Resorts San Luis Bay Inn - Studio
Retro English Mansion Sleeps 35 Gardens
Fridge, microwave, oven, stovetop

Retro English Mansion Sleeps 35 Gardens

9.8 out of 10, Exceptional, (24)
"Great house. Fascinating pictures and furnishings everywhere. Owner was very responsive to the couple of questions that we had."
Retro English Mansion Sleeps 35 Gardens
Villa Allegria-Pool/Spa Basketball, Sleeps 8!
Terrace/patio

Villa Allegria-Pool/Spa Basketball, Sleeps 8!

2.0 star property
Villa Allegria-Pool/Spa Basketball, Sleeps 8!
Casa Kaleidoscope-Amazing View*Eco-friendly design
Interior

Casa Kaleidoscope-Amazing View*Eco-friendly design

10.0 out of 10, Exceptional, (2)
"We were all impressed by the property and our experience. I may never stay in a hotel/Motel again. This property was awesome! "
Casa Kaleidoscope-Amazing View*Eco-friendly design
Diamond Resorts San Luis Bay Inn - Studio
Marina

Diamond Resorts San Luis Bay Inn - Studio

6.8 out of 10, (3)
"Loved the proximity to the beach and walking trails- an adult pool hour or 2 would be nice but plenty of chairs off away on the grass area to enjoy some peace and quiet! Super friendly staff"
Diamond Resorts San Luis Bay Inn - Studio
Villa in Wine Country, King Beds & Jacuzzi
Outdoor dining

Villa in Wine Country, King Beds & Jacuzzi

10.0 out of 10, Exceptional, (5)
"This home was more than perfect. My family and I enjoyed our time here. This home is a great size, the beds and bedding were comfortable. All the complimentary items was the perfect touch. With the pool, jacuzzi, large yard games, and fire pit you always have something to do and never have to leave the home. The kids absolutely loved the big pool and all the pool games and floaties that were provided. We will be booking again in the future."
The price is CA $586
CA $1,084 total
includes taxes & fees
Apr 29 - Apr 30
Villa in Wine Country, King Beds & Jacuzzi
4K Ranch @ 805 8+ acre Spanish Villa
Exterior

4K Ranch @ 805 8+ acre Spanish Villa

4K Ranch @ 805 8+ acre Spanish Villa
Diamond Resorts San Luis Bay Inn - 2 Bedroom Lockoff
Marina

Diamond Resorts San Luis Bay Inn - 2 Bedroom Lockoff

Diamond Resorts San Luis Bay Inn - 2 Bedroom Lockoff
Diamond Resorts San Luis Bay Inn - 1 Bedroom Deluxe
Marina

Diamond Resorts San Luis Bay Inn - 1 Bedroom Deluxe

Diamond Resorts San Luis Bay Inn - 1 Bedroom Deluxe
Diamond Resorts San Luis Bay Inn - 1 Bedroom
Marina

Diamond Resorts San Luis Bay Inn - 1 Bedroom

Diamond Resorts San Luis Bay Inn - 1 Bedroom
Diamond Resorts San Luis Bay Inn - 2 Bedroom
Marina

Diamond Resorts San Luis Bay Inn - 2 Bedroom

Diamond Resorts San Luis Bay Inn - 2 Bedroom
This is a Spacious Beauty and is a Villa on the Bluffs at the Rancho
Aerial view

This is a Spacious Beauty and is a Villa on the Bluffs at the Rancho

This is a Spacious Beauty and is a Villa on the Bluffs at the Rancho
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Los Osos

Pacific Plaza Resort
Condo4 409 | Terrace/patio

Pacific Plaza Resort

3.5 star property
8.6 out of 10, Excellent, (916)
"We stayed in October and were very pleased with the accommodations for the price and location. Easy walk to the beach and small but full kitchen for simple meals so we didn’t have to eat out every meal. "
Pacific Plaza Resort
Avila Pismo RV Resort and Campground
Free WiFi, bed sheets

Avila Pismo RV Resort and Campground

3.0 star property
9.0 out of 10, Wonderful, (9)
"We have never stayed in a mobile / tiny home cabin so it was outside our normal. The "cabin" we stayed in was small but functional. There are hiking trails around the property, swimming pool, and other activities within the campground. Easy driving distance to Avila Beach, Pismo Beach, and Port San Luis. The reception staff are gracious and very welcoming. An awesome two day stay for my spouse and self. "
The price is CA $169
CA $190 total
includes taxes & fees
Apr 6 - Apr 7
Avila Pismo RV Resort and Campground
SLO Brew Lofts
Mountain view

SLO Brew Lofts

4.0 star property
9.0 out of 10, Wonderful, (81)
"I had a medical emergency but my wife and kids enjoyed their stay. Added benefit was the coffee shop next door and bars."
The price is CA $343
CA $754 total
includes taxes & fees
Apr 7 - Apr 8
SLO Brew Lofts
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Why book your villa in Los Osos with Expedia?
We think organizing a vacation shouldn’t be complicated, so if you’re on the lookout for villas at a competitive price, Expedia delivers. Save those pennies and pick an all-inclusive stay, or splurge on a luxe villa to spoil the ones you love most. Our search filters make it easy to find an escape in Los Osos that suits you best.
How can I find cheap villas in Los Osos?
Expedia is here to help you easily locate cheap villas in Los Osos. Use our handy filter tool to select star rating, amenities and budget to refine your search and find an amazing place to stay in a matter of clicks.
What is there to do near my villa in Los Osos?
Los Osos has enough activities and sights to entertain you for weeks, beginning with Elfin Forest Preserve. Morro Dunes Natural Preserve, Los Osos Oaks State Reserve and Bluff Trail are other terrific attractions. If you’re lingering longer, Valencia Peak Trail and Morro Coast Audubon Society Sweet Springs Nature Preserve are nice finishing touches to your itinerary.