Lake City Vacation Rentals

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Vacation Rentals in Lake City

Cheerful home with plenty of privacy and entertainment room.
Fridge, microwave, oven, stovetop

Cheerful home with plenty of privacy and entertainment room.

8.4 out of 10, Very good, (19)
"Spacious home, with plenty of room for 6 adults. Just a heads-up, there's a sweet cat on the property. We found out a couple of days before, and let the owner know we had someone with a severe allergy. They made sure she wasn't able to come in the house, and we didn't have any trouble with reactions inside. The kitchen could use an update, but we there are plenty of dishes, utensils and spices available. Located on the edge of town, but still near plenty of food and grocery options. Having the...
Cheerful home with plenty of privacy and entertainment room.
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Fridge, microwave, oven, stovetop

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

10.0 out of 10, Exceptional, (10)
"10/10 highly recommend if your in the area and need a place to stay. Very comfy, cozy and at home feel. "
The price is CA $250
CA $423 total
includes taxes & fees
Dec 2 - Dec 3
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Oasis Located in the Heart of a Winery/ Halfway Point for Most Travelers
2 bedrooms, WiFi, bed sheets

Oasis Located in the Heart of a Winery/ Halfway Point for Most Travelers

9.6 out of 10, Exceptional, (24)
"Accommodated early arrival check in. Nice space and ample accommodations for four people. Easy to locate and access property."
The price is CA $175
CA $313 total
includes taxes & fees
Dec 5 - Dec 6
Oasis Located in the Heart of a Winery/ Halfway Point for Most Travelers
Family Retreat for vacations, weddings, family reunions and corporate retreats.
Property grounds

Family Retreat for vacations, weddings, family reunions and corporate retreats.

10.0 out of 10, Exceptional, (1)
"Great location and property."
Family Retreat for vacations, weddings, family reunions and corporate retreats.
Hickory Haven 3Br Elegant Downtown Hidden Gem
Interior

Hickory Haven 3Br Elegant Downtown Hidden Gem

9.4 out of 10, Exceptional, (12)
"Our stay in Florence at this VRBO was simply amazing! Cleanliness was 10/10. Amenities were great! It was fully stocked . Game room was an added plus! It was comfortable and very well decorated and very well put together for the comfort of all who desires a home filled environment. The character of this home was superb! My family and I really enjoyed ourselves! We will definitely choose to stay here again . Host communication was excellent! Check in and out was easy an convenient."
Hickory Haven 3Br Elegant Downtown Hidden Gem
Creekside Country Cottage- minutes away from I-95
Interior

Creekside Country Cottage- minutes away from I-95

10.0 out of 10, Exceptional, (3)
"Quintessential knotty pine cottage directly on the lake shore. A classic, evidencing the effort to make it so!"
The price is CA $351
CA $661 total
includes taxes & fees
Dec 2 - Dec 3
Creekside Country Cottage- minutes away from I-95
Pineapple House: Historic. Southern Charm. Walk Downtown.
Smart TV

Pineapple House: Historic. Southern Charm. Walk Downtown.

9.4 out of 10, Exceptional, (13)
"The property was very clean and had nice decor. Bed was very comfortable and liked that there was a lot of towels for us to use. Communication with the host was excellent. They responded right away to our questions prior to check in. Check in was a breeze. The kitchen had everything we needed. The note from the host was a nice surprise. Location was convenient in that it was close to restaurants and the hospital. Neighborhood was quiet."
Pineapple House: Historic. Southern Charm. Walk Downtown.
Quaint Bungalow in Historic Downtown Florence
Smart TV, books

Quaint Bungalow in Historic Downtown Florence

10.0 out of 10, Exceptional, (11)
"The pictures on the VRBO app does not do this charming home justice, upon arrival the pink door alone was inviting but after opening the door, the oooh’s and the ahhhh’s started! You walk in and you are grinning from ear to ear the decor of this crafted 1930’s home was so beautiful, the hosts went into to great detail remodeling and updating the home but keeping it simple with clean lines and colors the decorator needs to teach me this skill! I did take pictures of everything I liked! The beds...
Quaint Bungalow in Historic Downtown Florence
Cozy 4-bedroom house with WiFi, AC in charming Florence
Microwave, dishwasher

Cozy 4-bedroom house with WiFi, AC in charming Florence

2.0 star property
7.0 out of 10, Good, (2)
"Excellent accommodations,. More than satisfied. "
Cozy 4-bedroom house with WiFi, AC in charming Florence
Walking distance from one of South Carolina's top Medical centers.
Fridge, microwave, oven, stovetop

Walking distance from one of South Carolina's top Medical centers.

9.8 out of 10, Exceptional, (31)
"Great accommodations and thoughtful details. Absolutely loved it!"
The price is CA $163
CA $292 total
includes taxes & fees
Dec 2 - Dec 3
Walking distance from one of South Carolina's top Medical centers.
Great Home in the Greater Florence Area
Smart TV

Great Home in the Greater Florence Area

10.0 out of 10, Exceptional, (3)
"Thank you so much for sharing your home with us for the last 3 months. Everything was wonderful and comfortable stay. "
Great Home in the Greater Florence Area
Townhouse in Florence SC closed to MUSC medical center.
Smart TV

Townhouse in Florence SC closed to MUSC medical center.

Townhouse in Florence SC closed to MUSC medical center.
Camping it is!
Miscellaneous

Camping it is!

Camping it is!
Comfy Townhome~ Modern Farmhouse with Full Office!
Fridge, blender, dining tables

Comfy Townhome~ Modern Farmhouse with Full Office!

10.0 out of 10, Exceptional, (2)
"I had a very nice stay in Florence at this property. I was working from home through the week and the office setup was perfect."
Comfy Townhome~ Modern Farmhouse with Full Office!
☑️Cozy Work Friendly Condo in Florence☑️
Microwave, cookware/dishes/utensils

☑️Cozy Work Friendly Condo in Florence☑️

9.4 out of 10, Exceptional, (8)
"Everything was great,the rooms were clean there was a problem with knats and a there was a roach in the kitchen 😳 but overall the place was nice travis was kind i didn't really want to mention these,but i believe you can't fix a problem if you don't know about it again i really enjoyed my stay."
The price is CA $318
CA $490 total
includes taxes & fees
Dec 1 - Dec 2
☑️Cozy Work Friendly Condo in Florence☑️
2B/1.5 Bath Brand new Townhouse Closed to MUSC
Fridge, microwave, oven, stovetop

2B/1.5 Bath Brand new Townhouse Closed to MUSC

2.0 star property
10.0 out of 10, Exceptional, (1)
"Great property, very clean and everything you need is provided. "
2B/1.5 Bath Brand new Townhouse Closed to MUSC
Luxury stay at 4 bedroom house
Fridge, microwave, oven, stovetop

Luxury stay at 4 bedroom house

9.0 out of 10, Wonderful, (2)
"We went to Florence for a family reunion and wanted a place close by. The house is fine but slightly strange in its decor. It's perfectly fine, safe, and the host responds to questions very quickly,"
Luxury stay at 4 bedroom house
Stylish 3B/2Ba Condo-Sleeps 6. Close to Florence Center, Shopping & Airport.
Living area

Stylish 3B/2Ba Condo-Sleeps 6. Close to Florence Center, Shopping & Airport.

Stylish 3B/2Ba Condo-Sleeps 6. Close to Florence Center, Shopping & Airport.
Charming Brand NEW 3B/2bathroom house closed by to all shopping and MUSC
Fridge, microwave, oven, stovetop

Charming Brand NEW 3B/2bathroom house closed by to all shopping and MUSC

2.0 star property
Charming Brand NEW 3B/2bathroom house closed by to all shopping and MUSC
Work Friendly House Downtown Florence
Property grounds

Work Friendly House Downtown Florence

Work Friendly House Downtown Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other types of properties in Lake City you may be interested in

The Inn at the Crossroads
Exterior

The Inn at the Crossroads

2.0 star property
9.4 out of 10, Exceptional, (639)
"Quiet"
The price is CA $213
CA $239 total
includes taxes & fees
Dec 27 - Dec 28
The Inn at the Crossroads
Quality Inn & Suites
Lobby

Quality Inn & Suites

2.5 star property
7.2 out of 10, Good, (141)
"Great stay "
The price is CA $140
CA $157 total
includes taxes & fees
Dec 16 - Dec 17
Quality Inn & Suites
Days Inn by Wyndham Lake City
Lobby

Days Inn by Wyndham Lake City

2.0 star property
6.4 out of 10, (226)
"Good "
The price is CA $157
CA $176 total
includes taxes & fees
Dec 6 - Dec 7
Days Inn by Wyndham Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Beautiful view of the beach with palm trees

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Frequently asked questions

Can I find a vacation rental in Lake City?

Yes, we offer vacation rentals in Lake City near Moore Farms Botanical Garden, or you can choose a secluded option if you want a relaxing stay. Visitors to Lake City speak positively about the lakeside and restaurants in this destination. Make sure you have time to check out the shopping and parks during your trip.

What are some of the best vacation rentals that Lake City has to offer?

Cheerful home with plenty of privacy and entertainment room.: This vacation home rental outside of Lake City offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and an arcade game room.

What can I see and do in Lake City?

Lions Park and Moore Farms Botanical Garden are a couple of lovely local spots to get outside and enjoy nature. The Country Club at Lake City and Lynches Lake Historical Society are other places to visit while you're in town.

What are vacation rentals like in Lake City?

Vacation rentals are private properties you can stay in for a couple days or more in Lake City. Vacation rentals feature amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a clean environment, vacation rentals can offer a sense of seclusion away from public hotel elevators and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for family trips or small group gatherings.