Lake City Vacation Rentals

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Vacation Rentals in Lake City

Cheerful home with plenty of privacy and entertainment room.

8.4 out of 10, Very good, (20)
"Spacious home, with plenty of room for 6 adults. Just a heads-up, there's a sweet cat on the property. We found out a couple of days before, and let the owner know we had someone with a severe allergy. They made sure she wasn't able to come in the house, and we didn't have any trouble with reactions inside. The kitchen could use an update, but we there are plenty of dishes, utensils and spices available. Located on the edge of town, but still near plenty of food and grocery options. Having the...
Cheerful home with plenty of privacy and entertainment room.

Oasis Located in the Heart of a Winery/ Halfway Point for Most Travelers

9.6 out of 10, Exceptional, (25)
"Accommodated early arrival check in. Nice space and ample accommodations for four people. Easy to locate and access property."
The price is CA $179
CA $318 total
includes taxes & fees
Jan 14 - Jan 15
Oasis Located in the Heart of a Winery/ Halfway Point for Most Travelers

Walking distance from one of South Carolina's top Medical centers.

9.8 out of 10, Exceptional, (34)
"We stayed at this great home when we came to Florence for a race. It was roomy and comfortable and perfect for the four of us. I love the big open kitchen! It was convenient to the places we needed to be and we felt safe and secure in the neighborhood. The host was excellent in messaging and making sure we had everything we needed, and the home was very well stocked. We’ve decided this will be where we stay every time we come down for a race now. Highly recommend! "
The price is CA $168
CA $306 total
includes taxes & fees
Jan 22 - Jan 23
Walking distance from one of South Carolina's top Medical centers.

Family Retreat for vacations, weddings, family reunions and corporate retreats.

10.0 out of 10, Exceptional, (1)
"Great location and property."
Family Retreat for vacations, weddings, family reunions and corporate retreats.

Charming 3-bedroom house in Florence, SC

Charming 3-bedroom house in Florence, SC

Charming 3-bedroom home in Florence near McLeod Hospital and downtown.

10.0 out of 10, Exceptional, (2)
Charming 3-bedroom home in Florence near McLeod Hospital and downtown.

Hickory Haven 3Br Elegant Downtown Hidden Gem

9.6 out of 10, Exceptional, (14)
"Hickory Haven was absolutely beautiful home, clean smelled fresh and you walk in amazed, it doesn’t look that big from the outside but it was perfect huge inside! Yes my initial thought was “oh my” the neighborhood however no issues it was quite and the neighbors were nice! These craft homes are getting make overs but one house at a time, that it why you can’t judge a book by the cover! No one bothered us I do wish the road was wider but that didn’t make us unhappy, the home was cute and...
Hickory Haven 3Br Elegant Downtown Hidden Gem

Creekside Country Cottage- minutes away from I-95

10.0 out of 10, Exceptional, (4)
"Quintessential knotty pine cottage directly on the lake shore. A classic, evidencing the effort to make it so!"
The price is CA $359
CA $679 total
includes taxes & fees
Jan 20 - Jan 21
Creekside Country Cottage- minutes away from I-95

Pineapple House: Historic. Southern Charm. Walk Downtown.

9.4 out of 10, Exceptional, (13)
"The property was very clean and had nice decor. Bed was very comfortable and liked that there was a lot of towels for us to use. Communication with the host was excellent. They responded right away to our questions prior to check in. Check in was a breeze. The kitchen had everything we needed. The note from the host was a nice surprise. Location was convenient in that it was close to restaurants and the hospital. Neighborhood was quiet."
Pineapple House: Historic. Southern Charm. Walk Downtown.

Quaint Bungalow in Historic Downtown Florence

10.0 out of 10, Exceptional, (11)
"The pictures on the VRBO app does not do this charming home justice, upon arrival the pink door alone was inviting but after opening the door, the oooh’s and the ahhhh’s started! You walk in and you are grinning from ear to ear the decor of this crafted 1930’s home was so beautiful, the hosts went into to great detail remodeling and updating the home but keeping it simple with clean lines and colors the decorator needs to teach me this skill! I did take pictures of everything I liked! The beds...
Quaint Bungalow in Historic Downtown Florence

Great Home in the Greater Florence Area

9.6 out of 10, Exceptional, (5)
"Nice location and home. Owner was very responsive and accommodating. Matt promptly addressed our initial concerns after checkin. I would consider this home again for potential future bookings. "
Great Home in the Greater Florence Area

Townhouse in Florence SC closed to MUSC medical center.

Townhouse in Florence SC closed to MUSC medical center.

Comfy Townhome~ Modern Farmhouse with Full Office!

10.0 out of 10, Exceptional, (2)
"I had a very nice stay in Florence at this property. I was working from home through the week and the office setup was perfect."
Comfy Townhome~ Modern Farmhouse with Full Office!

☑️Cozy Work Friendly Condo in Florence☑️

9.0 out of 10, Wonderful, (9)
"Everything was great,the rooms were clean there was a problem with knats and a there was a roach in the kitchen 😳 but overall the place was nice travis was kind i didn't really want to mention these,but i believe you can't fix a problem if you don't know about it again i really enjoyed my stay."
The price is CA $326
CA $501 total
includes taxes & fees
Jan 20 - Jan 21
☑️Cozy Work Friendly Condo in Florence☑️

Charming Brand NEW 3B/2bathroom house closed by to all shopping and MUSC

2.0 star property
10.0 out of 10, Exceptional, (1)
Charming Brand NEW 3B/2bathroom house closed by to all shopping and MUSC

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

10.0 out of 10, Exceptional, (11)
"10/10 highly recommend if your in the area and need a place to stay. Very comfy, cozy and at home feel. "
The price is CA $255
CA $432 total
includes taxes & fees
Jan 14 - Jan 15
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

2B/1.5 Bath Brand new Townhouse Closed to MUSC

2.0 star property
10.0 out of 10, Exceptional, (1)
"Great property, very clean and everything you need is provided. "
2B/1.5 Bath Brand new Townhouse Closed to MUSC

Camping it is!

Camping it is!

Luxury stay at 4 bedroom house

9.0 out of 10, Wonderful, (2)
"We went to Florence for a family reunion and wanted a place close by. The house is fine but slightly strange in its decor. It's perfectly fine, safe, and the host responds to questions very quickly,"
Luxury stay at 4 bedroom house

Stylish 3B/2Ba Condo-Sleeps 6. Close to Florence Center, Shopping & Airport.

Stylish 3B/2Ba Condo-Sleeps 6. Close to Florence Center, Shopping & Airport.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other types of properties in Lake City you may be interested in

The Inn at the Crossroads

2.0 star property
9.4 out of 10, Exceptional, (653)
"Nice renovation. Nice location. Great experience. I recommend…"
The price is CA $215
CA $241 total
includes taxes & fees
Jan 12 - Jan 13
The Inn at the Crossroads

Quality Inn & Suites

2.5 star property
7.2 out of 10, Good, (143)
"The updates and very quiet. "
The price is CA $163
CA $182 total
includes taxes & fees
Jan 20 - Jan 21
Quality Inn & Suites

Days Inn by Wyndham Lake City

2.0 star property
6.4 out of 10, (226)
"Good "
The price is CA $165
CA $184 total
includes taxes & fees
Jan 12 - Jan 13
Days Inn by Wyndham Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Can I find a vacation rental in Lake City?

Yes, we offer vacation rentals in Lake City near Moore Farms Botanical Garden, or you can choose a secluded option if you want a relaxing stay. Visitors to Lake City speak positively about the lakeside and restaurants in this destination. Make sure you have time to check out the shopping and parks during your trip.

What are some of the best vacation rentals that Lake City has to offer?

Cheerful home with plenty of privacy and entertainment room.: This vacation home rental outside of Lake City offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and an arcade game room.

What can I see and do in Lake City?

Lions Park and Ronald E. McNair Life History Center are a couple of lovely local spots to get outside and enjoy nature. Moore Farms Botanical Garden and Lynches Lake Historical Society are other places to visit while you're in town.

What are vacation rentals like in Lake City?

Vacation rentals are private properties you can stay in for a couple days or more in Lake City. Vacation rentals feature amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a clean environment, vacation rentals can offer a sense of seclusion away from public hotel elevators and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for family trips or small group gatherings.