Photo by Michele Butts

Find hotels in La Mesa, CA from CA $109

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Top 10 La Mesa hotels and places to stay

Wyndham Garden San Diego Near SeaWorld

3.0 star property
7.2 out of 10, Good, (3645)
"They charge me $20 dollars a day for parking, this is ridiculous, this area it’s not Disneyland "
The price is CA $142
CA $160 total
includes taxes & fees
Dec 23 - Dec 24
Wyndham Garden San Diego Near SeaWorld

Paradise Point Resort & Spa

4.0 star property
8.6 out of 10, Excellent, (1968)
"We loved our stay and can’t wait to come back in the summer !!"
The price is CA $257
CA $360 total
includes taxes & fees
Dec 30 - Dec 31
Paradise Point Resort & Spa

The Dana on Mission Bay

3.5 star property
8.8 out of 10, Excellent, (2956)
"Excellent place for a great price."
The price is CA $214
CA $241 total
includes taxes & fees
Jan 1 - Jan 2, 2025
The Dana on Mission Bay

Wyndham San Diego Bayside

4.0 star property
8.2 out of 10, Very good, (5544)
"The Bayview is nine and it is close to the city center."
The price is CA $218
CA $246 total
includes taxes & fees
Jan 2 - Jan 3, 2025
Wyndham San Diego Bayside

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
7.6 out of 10, Good, (2009)
"Like cleaning room pool areas very clean and comfortable nice very close to malls customers service was great "
The price is CA $128
CA $144 total
includes taxes & fees
Dec 24 - Dec 25
Days Inn by Wyndham San Diego Hotel Circle

Lafayette Hotel & Club

4.0 star property
9.2 out of 10, Wonderful, (507)
"The Lafayette is over the top and beyond imagination especially during the holidays! Retro diner, poolside service, music venue, amazing restaurant, and private bowling alley ... and the rooms - oo la la. Definitely a young hip vibe, but super friendly staff. "
The price is CA $289
CA $325 total
includes taxes & fees
Jan 12 - Jan 13, 2025
Lafayette Hotel & Club

Hilton San Diego Mission Valley

4.0 star property
7.8 out of 10, Good, (1363)
"Another great stay at Hilton. "
The price is CA $180
CA $202 total
includes taxes & fees
Dec 29 - Dec 30
Hilton San Diego Mission Valley

Comfort Inn Sea World Area

3.5 star property
8.6 out of 10, Excellent, (1291)
"Everything was good, the bed and pillows pretty comfortable and clean!!! The only thing is that the area around is not thaaat gooood there’s a few homeless close by but nothing that bad! I’ll stay there again for sure "
The price is CA $142
CA $160 total
includes taxes & fees
Jan 2 - Jan 3, 2025
Comfort Inn Sea World Area

Bay Club Hotel & Marina

3.5 star property
9.0 out of 10, Wonderful, (2337)
"2 of 3 nights when taking shower the water would not get hot; cold or like warm. Otherwise the visit was good."
The price is CA $177
CA $200 total
includes taxes & fees
Jan 11 - Jan 12, 2025
Bay Club Hotel & Marina

Kings Inn San Diego

2.5 star property
8.8 out of 10, Excellent, (3088)
"My wife and I had a very nice stay. People were very friendly, restaurant's were very convenient and food was very tasty. Room was clean and service was outstanding. Would definitely stay there again."
The price is CA $137
CA $154 total
includes taxes & fees
Dec 23 - Dec 24
Kings Inn San Diego

Embassy Suites by Hilton San Diego La Jolla

4.0 star property
8.8 out of 10, Excellent, (1313)
"Very quite"
The price is CA $217
CA $245 total
includes taxes & fees
Jan 11 - Jan 12, 2025
Embassy Suites by Hilton San Diego La Jolla

Best Western Plus Marina Gateway Hotel

3.5 star property
9.0 out of 10, Wonderful, (2974)
"Not only was everything great, the staff was amazing! From the two young ladies in the morning, to the two gentlemen in the evening and the cleaning staff- it appeared that everyone was there to serve me, and as a guest that feels awesome. The location was great, the room was clean, the lobby and outside were comfortable.... I won't be looking for any other places to stay on my next visits to SD."
The price is CA $193
CA $212 total
includes taxes & fees
Jan 2 - Jan 3, 2025
Best Western Plus Marina Gateway Hotel

Holiday Inn Express San Diego Downtown, an IHG Hotel

2.5 star property
8.4 out of 10, Very good, (1210)
"nice"
The price is CA $200
CA $225 total
includes taxes & fees
Dec 23 - Dec 24
Holiday Inn Express San Diego Downtown, an IHG Hotel

Omni San Diego Hotel

4.0 star property
9.0 out of 10, Wonderful, (1760)
"Love the hotel. Hate the Tourist Destination Fee and feel the valet parking at $65 is too high. That said, it’s wonderfully located. "
The price is CA $206
CA $296 total
includes taxes & fees
Dec 23 - Dec 24
Omni San Diego Hotel

The Wayfarer San Diego

4.0 star property
9.2 out of 10, Wonderful, (1264)
"Excellent location, close to everything! Clean and super cute! The view was unbelievable. We will definitely stay here again. "
The price is CA $241
CA $272 total
includes taxes & fees
Jan 5 - Jan 6, 2025
The Wayfarer San Diego

Comfort Inn San Diego Old Town

2.5 star property
8.0 out of 10, Very good, (1408)
"Convenient location with good restaurant nearby, walking distamce to trolley and airport shuttle. The room size is ok. The bed and sheets are clean but towels are a ttle old. The breakfast is clean and includes fresh fruits and waffle. No room service. The courtyard is cute. Although it's close to highway, the noise is not bothering. "
The price is CA $145
CA $163 total
includes taxes & fees
Jan 4 - Jan 5, 2025
Comfort Inn San Diego Old Town

Bahia Resort Hotel

3.5 star property
8.6 out of 10, Excellent, (1441)
"Well maintain, we had a late night swim at the heated pool and one of the employee came to make sure the temperature was too our liking. "
The price is CA $221
CA $320 total
includes taxes & fees
Jan 5 - Jan 6, 2025
Bahia Resort Hotel

Palihotel San Diego

4.0 star property
8.6 out of 10, Excellent, (1009)
"Great location in the heart of Gaslamp."
The price is CA $151
CA $210 total
includes taxes & fees
Dec 23 - Dec 24
Palihotel San Diego

San Diego Mission Bay Resort

4.0 star property
8.2 out of 10, Very good, (1108)
"Beautiful location, but a bathroom door that doesn’t lock or stay closed is not good for more than one person. The thermostat obviously didn’t work as we set it to 85 to warm up the room and it never warmed up. Parking for one night out front was $43 so that was outrageous! Thought it was strange that water wasn’t offered given the amount I spent to stay there..unless I wanted to pay $7 a bottle..and still haven’t gotten the checkout email.."
The price is CA $271
CA $369 total
includes taxes & fees
Dec 23 - Dec 24
San Diego Mission Bay Resort

California Suites Hotel

2.0 star property
7.4 out of 10, Good, (1700)
"The property was nice and offered really nice amenities. Only downside was they are doing construction so you hear that every morning and most of the day. Other than that Id stay there again."
The price is CA $154
CA $174 total
includes taxes & fees
Dec 23 - Dec 24
California Suites Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place for a stay in La Mesa?

Best Western Plus La Mesa San Diego is a favorite property for Expedia customers. This hotel offers free breakfast and an outdoor pool. Reviews from our site also recommend Holiday Inn Express La Mesa Near SDSU, an IHG Hotel and Motel 6 La Mesa, CA as top choices for your visit. See all available top hotels, or vacation rentals in La Mesa.

What's the top vacation rental in La Mesa?

Adorable Spanish style casita in fantastic area of Historic North Park: This vacation home near La Mesa is located by the ocean and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Make the most of the selection of games in this rental home to help you unwind. See all vacation rentals in La Mesa.

If I need to cancel my hotel reservation in La Mesa, will I receive a refund?

Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.

Where can I learn more about changing or cancelling my trip to La Mesa?

To find more details about changing or cancelling your trip to La Mesa, head over to our customer service page.

What's the best place to stay on a budget in La Mesa?

Based on our traveler reviews, Motel 6 La Mesa, CA - San Diego is a top choice for a less expensive stay. View all budget hotels in La Mesa.

What's the best place to stay for a family vacation in La Mesa?

Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is a hotel with an outdoor pool and laundry facilities, and it's a top choice on Expedia for families. The Best of San Diego! Room to Enjoy, Relax and Recharge!! is another good option for your stay with the kids. Kids of all ages will also enjoy a visit to Computer Museum of America. Find more child-friendly accommodations in La Mesa.

What's the best place to stay for a romantic getaway to La Mesa?

The Best of San Diego! Room to Enjoy, Relax and Recharge!! is a favorite guesthouse for couples, and features Smart TVs and refrigerators. See all romantic hotels in La Mesa.

What is the top LGBTQ-friendly hotel in La Mesa?

Heritage Inn La Mesa is a top LGBTQ-friendly hotel that features free WiFi and free parking. Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is another good option for your trip. See all available hotels listed as LGBTQ-friendly in La Mesa.

What's the best pet-friendly accommodation in La Mesa?

Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is a top hotel for people traveling with their pets, and offers an outdoor pool and free WiFi for its human guests. Two other good options for you and your pet's trip include Motel 6 La Mesa, CA and Motel 6 La Mesa, CA - San Diego. See more pet-friendly hotel accommodations in La Mesa.

Where is the best hotel to stay close to Computer Museum of America?

Lodge of La Mesa (A Quiet Hotel For Adults Only) is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free WiFi. It's located just a short 1 mi (1.6 km) from Computer Museum of America. Other good choices close by include Motel 6 San Diego - La Mesa and Days Inn & Suites by Wyndham San Diego SDSU.

What's the best hotel for a beach vacation in La Mesa?

Lodge of La Mesa (A Quiet Hotel For Adults Only) is a top hotel for a beach vacation, and features free breakfast and free WiFi. Other good choices for your stay near the beach include Days Inn & Suites by Wyndham San Diego SDSU and Heritage Inn La Mesa. Head to Coronado Beach or Mission Bay for some quality time by the water.

What are some accommodations with pools in La Mesa?

Holiday Inn Express La Mesa Near SDSU, an IHG Hotel is a top hotel with a pool, free WiFi, and in-room flat-screen TVs. View all hotels with pools in La Mesa.

What is the best spa hotel in La Mesa?

Best Western Plus La Mesa San Diego is a top spa hotel featuring a fitness center and an outdoor pool. Kick back and relax in the spa tub. See all spa hotels in La Mesa.

What's the top hotel in La Mesa with an on-site water park or a water park nearby?

Quite Peaceful Mountain Retreat is a popular vacation home featuring water park access, an outdoor pool, and in-room kitchens. Another top water park hotel you might want to consider is Top-secret Luxury on Hillside Estate Property, Minutes From Downtown San Diego.

What is the best hotel near San Diego International Airport (SAN)?

Sheraton San Diego Hotel and Marina is a popular 4-star hotel featuring a marina and 3 outdoor pools. It's located a short 0.4 mi (0.6 km) from San Diego Intl. Airport. Other places to stay near the airport are  Hampton Inn & Suites San Diego Airport Liberty Station and Wyndham San Diego Bayside.

What is staying in La Mesa like?

Families will find kid-friendly activities in La Mesa, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its shopping, zoo, and entertainment choices. Around the area, top sights include San Diego Zoo, San Ysidro Border Crossing, and Balboa Park. In La Mesa, there are 152 hotels and other accommodations to choose from. Find out more about La Mesa.

What should I see while I'm in La Mesa?

A couple of favorite places to visit are Mount Helix Park and Computer Museum of America. You'll also find San Diego Zoo and San Ysidro Border Crossing in the area. Check out what more to see and do in Expedia's La Mesa guide.

What's the best way to get around La Mesa?

You can take advantage of metro transit at La Mesa Boulevard Station, Spring St Trolley Station, and 70th St. Trolley Station. If you want to venture out around the area, you may want a rental car in La Mesa for your journey.

What's the seasonal weather like in La Mesa?

The hottest months are usually August and September with an average temp of 72°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for La Mesa is 12 inches.