Find hotels in La Mesa from CA $31

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check La Mesa hotel prices

Tomorrow night
This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top 10 La Mesa hotels and places to stay

Hotel Posada Comala
3.0 star property
8.4 out of 10, Very good, (122)
"Excelente ubicación! A unas cuadras del centro de Comala y con vista a una área arbolada y el río. "
The price is CA $39
CA $47 total
includes taxes & fees
Nov 23 - Nov 24
Hotel Posada Comala
Hotel Casa Alvarada
3.0 star property
9.2 out of 10, Wonderful, (60)
"We had a wonderful stay in this charming, family run hacienda. The room was well appointed, the bed comfortable and the shower roomy and with good temperature. There was coffee in the room. Our only slight disappointment was lack of breakfast but we found a fantastic restaurant nearby. The location is just a short walk from the plaza, yet it was a quiet neighborhood. Perhaps best of all was a guided tour we took with Jupiter, the fantastically knowledgeable owner "
The price is CA $67
CA $79 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Casa Alvarada
La Paranera Hotel & Relax
3.5 star property
9.8 out of 10, Exceptional, (41)
"Amazing property! Can’t wait to be back!! 5 star all the way around ! "
The price is CA $188
CA $224 total
includes taxes & fees
Nov 22 - Nov 23
La Paranera Hotel & Relax
Quinta Comala
2.5 star property
9.2 out of 10, Wonderful, (23)
"A great find in Comala. Economically priced, nice refreshing pool. Just 2 blocks from the main street. Clean, large rooms, helpful staff."
The price is CA $82
CA $98 total
includes taxes & fees
Nov 24 - Nov 25
Quinta Comala
Hostal Casa Blanca
2.5 star property
7.6 out of 10, Good, (4)
"Los cuartos son muy básicos pero eso si muy limpios El inconveniente que veo es que es un cuarto caliente y su ventilador es muy pequeño y casi no echa aire por lo que uno no puede descansar bien No cuentan con AA por la zona en que se encuentran (Colima)"
The price is CA $37
CA $45 total
includes taxes & fees
Dec 16 - Dec 17
Hostal Casa Blanca
COMALITAS HOTEL Y CAFE
3.0 star property
4.0 out of 10, (1)
The price is CA $81
CA $96 total
includes taxes & fees
Nov 22 - Nov 23
COMALITAS HOTEL Y CAFE
Cabaña Madalena
2.5 star property
The price is CA $138
CA $164 total
includes taxes & fees
Nov 22 - Nov 23
Cabaña Madalena
Cabanas del Volcan
2.0 star property
Cabanas del Volcan
Beautiful home in charming town of Cofradia
10.0 out of 10, Exceptional, (3)
"The house was beautiful! It was so nicely decorated. Having a bathroom for each bedroom was awesome. The privacy very appreciated. The garden..oh my what a beautiful place to sit and unwind and listen to the birds. It was such a great house!"
The price is CA $77
CA $117 total
includes taxes & fees
Nov 29 - Nov 30
Beautiful home in charming town of Cofradia
Casa de Campo con Increíble Vista al Volcán de Colima y un Clima Excepcional.!
2.0 star property
Casa de Campo con Increíble Vista al Volcán de Colima y un Clima Excepcional.!
San Gabriels House at Chapalita Neighborhood
San Gabriels House at Chapalita Neighborhood
San Gabriel's House at Guadalajara, Jalisco, Mexico
San Gabriel's House at Guadalajara, Jalisco, Mexico
UNMATCHED AMENITIES in Guadalajara, Jalisco, Mexico
UNMATCHED AMENITIES in Guadalajara, Jalisco, Mexico
San Gabriels House at Chapalita
San Gabriels House at Chapalita
San Gabriels House at Chapalita, Guadalajara, Jalisco, Mexico
San Gabriels House at Chapalita, Guadalajara, Jalisco, Mexico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in La Mesa
Save an average of 15% on thousands of hotels when you're signed in
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until December 4 with our Black Friday deals. Stay by December 15, 2025.

Frequently asked questions

What's the best place to stay in La Mesa?

Based on our traveler data, Chalet de Colombo Hotel is one of the top choices for your stay. This ranch offers free parking and free WiFi. Two other options for your visit to the area are Hotel Zapotlan and Gran Casa Sayula Hotel & Spa. See all available top hotels, or vacation rentals in La Mesa.

What are some of the best vacation home rentals in La Mesa?

Finca El Campanario: This vacation home near La Mesa offers a garden and a barbecue grill to help you feel comfortable in your new surroundings. Kitchen amenities include a fridge, an oven, and a microwave. See all vacation rentals in La Mesa.

If I need to cancel my hotel reservation in La Mesa, will I receive a refund?

Yes, most hotel room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.

Where can I learn more about changing or cancelling my trip to La Mesa?

For more details about rescheduling or cancelling your trip to La Mesa, head over to our customer service page.

What are some accommodations with pools in La Mesa?

Gran Casa Sayula Hotel & Spa: Offers a full-service spa, an outdoor pool, and free parking. Hotel Colón and Hacienda De San Antonio are two additional hotels that feature an onsite pool. View all hotels with pools in La Mesa.

What's it like to stay in La Mesa?

Travelers to La Mesa will find plenty to explore and enjoy. There are 24 hotels and other accommodations in the surrounding area. Find out more about La Mesa.

What should I do while I'm visiting La Mesa?

Places to visit in the wider area include Laguna de Ciudad Guzman, Volcan Nevado de Colima National Park, and Las Penas Ecological Park. You'll also find Volcano of Colima and Municipal Garden in the area. Check out what more to see and do in Expedia's La Mesa guide.

What's the seasonal weather like in La Mesa?

The hottest months are usually May and April with an average temp of 70°F, while the coldest months are January and February with an average of 63°F. The rainiest months in La Mesa are August, July, September, and June, with each month seeing an average of 14 inches of rainfall.