Uptown - Upper Duval

Key West

Key West Butterfly and Nature Conservatory showing flowers, animals and zoo animals
Key West Butterfly and Nature Conservatory showing zoo animals, flowers and animals
South Beach featuring a sandy beach and a coastal town as well as a large group of people
South Beach which includes a luxury hotel or resort, swimming and a beach
Key West Butterfly and Nature Conservatory featuring signage

Popular places to visit

Southernmost Point

Southernmost Point

4/5(160 reviews)

Snap a memorable photograph from the edge of North America at this monumental landmark.

Southernmost Point
South Beach

South Beach

4/5(52 reviews)

The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

South Beach
Key West Butterfly and Nature Conservatory featuring zoo animals, animals and food

Key West Butterfly and Nature Conservatory

4.5/5(19 reviews)

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

Key West Butterfly and Nature Conservatory

Things to do

Florida: Key West Overseas Highway Self-Driving Tour

Florida: Key West Overseas Highway App-Based Driving Audio Tour

CA $22
per traveller
76% of travellers recommend
Florida: Key West Overseas Highway App-Based Driving Audio Tour
Key West’s Old Town Treasures: A Self-Guided Audio Tour

Key West’s Old Town Treasures: A Self-Guided Audio Tour

CA $22
per adult
Key West’s Old Town Treasures: A Self-Guided Audio Tour
Bahama Village Walking Tour

Bahama Village Walking Tour

CA $43
per adult
Bahama Village Walking Tour
Key West History And Culture Walking Tour

Southernmost Key West History and Culture Small-Group Walking Tour

CA $58
per adult
Southernmost Key West History and Culture Small-Group Walking Tour
Florida Key West Self-Guided Walking Audio Tour

Florida Key West Self-Guided Walking Audio Tour Via App

CA $13
per traveller
Florida Key West Self-Guided Walking Audio Tour Via App
Climb the 88 stairs to the top of the Key West Lighthouse.

Maritime Village to Micro State: A Self Guided Tour of Key West

CA $17
per adult
Maritime Village to Micro State: A Self Guided Tour of Key West
See all activities in Key West

Uptown - Upper Duval Hotel Deals

Southernmost Beach Resort
Southernmost Beach Resort
4 out of 5
1319 Duval Street, Key West, FL
The price is CA $656 per night from Mar. 11 to Mar. 12
CA $656
CA $836 total
includes taxes & fees
Mar 11 - Mar 12
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,282 reviews)
"The location and grounds are fantastic. Plenty of places to eat within walking distance. The only downside was the roosters outside our door crowing at 6 am. I understand that they are protecting and literally all over the island, but there has to be a way to manage the noise better. We ran our bathroom ..."

Reviewed on Mar. 9, 2025

Southernmost Beach Resort
The Reach Key West, Curio Collection by Hilton
The Reach Key West, Curio Collection by Hilton
4 out of 5
1435 Simonton Street, Key West, FL
The price is CA $617 per night from Mar. 13 to Mar. 14
CA $617
CA $791 total
includes taxes & fees
Mar 13 - Mar 14
Stay at this 4-star beach hotel in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (888 reviews)
"Beautiful place and the staff were amazing! Will definitely return!"

Reviewed on Mar. 7, 2025

The Reach Key West, Curio Collection by Hilton
The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
The price is CA $444 per night from Mar. 11 to Mar. 12
CA $444
CA $564 total
includes taxes & fees
Mar 11 - Mar 12
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8/10 Very Good! (1,035 reviews)
"Nice place to stay, quiet and close to south end"

Reviewed on Mar. 9, 2025

The Southernmost Inn - Adults Only
Southwinds Motel
Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL
The price is CA $389 per night from Apr. 1 to Apr. 2
CA $389
CA $478 total
includes taxes & fees
Apr 1 - Apr 2
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,087 reviews)
"This was my 3rd time in Key West and the first time at Southwinds with my lifelong best friend of almost 50 years. Couldn’t have asked for better service, accommodations, location, comfort and all-around amazing! I highly recommend Southwinds. Definitely will return!"

Reviewed on Mar. 9, 2025

Southwinds Motel
Douglas House
Douglas House
3 out of 5
419 Amelia St, Key West, FL
The price is CA $457 per night from Mar. 30 to Mar. 31
CA $457
CA $533 total
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3-star guesthouse in Key West. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Duval Street and Ernest Hemingway Home ...
9.4/10 Exceptional! (34 reviews)
"Loved it. Great area. Lovely pool. Great staff."

Reviewed on Feb. 24, 2025

Douglas House
The Mansion on the Sea - Southernmost House in the USA
The Mansion on the Sea - Southernmost House in the USA
3 out of 5
1400 Duval Street, Key West, FL
The price is CA $789 per night from Mar. 19 to Mar. 20
CA $789
CA $932 total
includes taxes & fees
Mar 19 - Mar 20
Stay at this 3-star beach hotel in Key West. Enjoy free breakfast, room service, and parking (surcharge). Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,007 reviews)
"we loved mansion on the sea ! will definitely be back ps and the breakfast was outstanding!"

Reviewed on Mar. 8, 2025

The Mansion on the Sea - Southernmost House in the USA
See all 2,924 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

Key West Historic District

Old Town Key West

3.5/5(8 area reviews)

Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.

Old Town Key West
Key West featuring a marina, a coastal town and general coastal views

Downtown Key West

If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Downtown Key West
Harry S. Truman Little White House which includes a house and cycling

Bahama Village

Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
Clarence S. Higgs Memorial Beach Park which includes landscape views, tropical scenes and a sandy beach

Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
Audubon House and Tropical Gardens featuring a house

Key West Historic District

4.5/5(156 area reviews)

Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.

Key West Historic District
Great location for great pictures, very nice beach

White Street Gallery District

When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area.

White Street Gallery District

Uptown - Upper Duval

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