Uptown - Upper Duval

Key West
Key West Butterfly and Nature Conservatory showing flowers, animals and zoo animals
Key West Butterfly and Nature Conservatory showing zoo animals, flowers and animals
South Beach featuring a sandy beach and a coastal town as well as a large group of people
South Beach which includes a luxury hotel or resort, swimming and a beach
Key West Butterfly and Nature Conservatory featuring signage

Popular places to visit

Southernmost Point

Southernmost Point

4/5(160 reviews)

Snap a memorable photograph from the edge of North America at this monumental landmark.

Southernmost Point
South Beach

South Beach

4/5(52 reviews)

The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

South Beach
Key West Butterfly and Nature Conservatory featuring zoo animals, animals and food

Key West Butterfly and Nature Conservatory

4.5/5(19 reviews)

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

Key West Butterfly and Nature Conservatory

Things to do

Florida: Key West Overseas Highway Self-Driving Tour

Florida: Key West Overseas Highway App-Based Driving Audio Tour

CA $22
per traveller
76% of travellers recommend
Florida: Key West Overseas Highway App-Based Driving Audio Tour
Key West History And Culture Walking Tour

Southernmost Key West History and Culture Small-Group Walking Tour

CA $57
per adult
Southernmost Key West History and Culture Small-Group Walking Tour
Bahama Village Walking Tour

Bahama Village Walking Tour

CA $43
per adult
Bahama Village Walking Tour
Key West’s Old Town Treasures: A Self-Guided Audio Tour

Key West’s Old Town Treasures: A Self-Guided Audio Tour

CA $22
per adult
Key West’s Old Town Treasures: A Self-Guided Audio Tour
Florida Key West Self-Guided Walking Audio Tour

Florida Key West Self-Guided Walking Audio Tour Via App

CA $13
per traveller
Florida Key West Self-Guided Walking Audio Tour Via App
An Audio Guide of Key West’s Journey From Village to Micro State

An Audio Guide of Key West’s Journey From Village to Micro State

CA $17
per adult
An Audio Guide of Key West’s Journey From Village to Micro State
See all activities in Key West

Uptown - Upper Duval Hotel Deals

Southernmost Beach Resort
Southernmost Beach Resort
4 out of 5
1319 Duval Street, Key West, FL
The price is CA $647 per night from Jan. 8 to Jan. 9
CA $647
CA $825 total
includes taxes & fees
Jan 8 - Jan 9, 2025
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.4/10 Very Good! (2,202 reviews)
"We thoroughly enjoyed our stay! Beautiful property! Well maintained. Our room and bathroom were spacious areas. My daughter and I enjoyed yoga two mornings. Pools were nice and clean. The location of the resort is perfect! We were right on the water and yet walkable to many shops, attractions and ..."

Reviewed on Dec. 27, 2024

Southernmost Beach Resort
The Reach Key West, Curio Collection by Hilton
The Reach Key West, Curio Collection by Hilton
4 out of 5
1435 Simonton Street, Key West, FL
The price is CA $544 per night from Jan. 7 to Jan. 8
CA $544
CA $703 total
includes taxes & fees
Jan 7 - Jan 8, 2025
Stay at this 4-star beach hotel in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (834 reviews)
"Great hotel - must stay"

Reviewed on Dec. 26, 2024

The Reach Key West, Curio Collection by Hilton
The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
The price is CA $396 per night from Jan. 5 to Jan. 6
CA $396
CA $511 total
includes taxes & fees
Jan 5 - Jan 6, 2025
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8/10 Very Good! (1,008 reviews)
"We loved the pool, breakfast, and nightly happy hour. Thank you, thank you for using a lot of paper products versus plastic! Southernmost Inn is a champion for the environment!"

Reviewed on Dec. 27, 2024

The Southernmost Inn - Adults Only
Southwinds Motel
Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL
The price is CA $390 per night from Jan. 27 to Jan. 28
CA $390
CA $479 total
includes taxes & fees
Jan 27 - Jan 28, 2025
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,053 reviews)
"Great property super convenient"

Reviewed on Dec. 27, 2024

Southwinds Motel
Orchid Key Inn - Adults Only
Orchid Key Inn - Adults Only
3.5 out of 5
1004 Duval St, Key West, FL
The price is CA $703 per night from Jan. 6 to Jan. 7
CA $703
CA $791 total
includes taxes & fees
Jan 6 - Jan 7, 2025
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
9.8/10 Exceptional! (1,001 reviews)
"Fantastic atmosphere."

Reviewed on Dec. 28, 2024

Orchid Key Inn - Adults Only
The Mansion on the Sea - Southernmost House in the USA
The Mansion on the Sea - Southernmost House in the USA
3 out of 5
1400 Duval Street, Key West, FL
The price is CA $834 per night from Jan. 2 to Jan. 3
CA $834
CA $983 total
includes taxes & fees
Jan 2 - Jan 3, 2025
Stay at this 3-star beach hotel in Key West. Enjoy free breakfast, room service, and parking (surcharge). Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (998 reviews)
"The staff and management at this resort is very friendly and they go above and beyond to ensure you have nothing less than an amazing experience! My wife and I will be booking all of our vacations here and no where else forever, there isn’t enough space to describe the awesome experience and hospitality ..."

Reviewed on Dec. 23, 2024

The Mansion on the Sea - Southernmost House in the USA
See all 2,882 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

Key West Historic District

Old Town Key West

3.5/5(8 area reviews)

Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.

Old Town Key West
Key West featuring a marina, a coastal town and general coastal views

Downtown Key West

If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Downtown Key West
Harry S. Truman Little White House which includes a house and cycling

Bahama Village

Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
Clarence S. Higgs Memorial Beach Park which includes landscape views, tropical scenes and a sandy beach

Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
Audubon House and Tropical Gardens featuring a house

Key West Historic District

4.5/5(156 area reviews)

Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.

Key West Historic District
Great location for great pictures, very nice beach

White Street Gallery District

When in White Street Gallery District, you can plan a visit to Duval Street and Saint Mary Star of the Sea, some noteworthy sights in the nearby area.

White Street Gallery District

Uptown - Upper Duval

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