Uptown - Upper Duval

Key West

Key West Butterfly and Nature Conservatory showing flowers, animals and zoo animals
Key West Butterfly and Nature Conservatory showing zoo animals, flowers and animals
South Beach featuring a sandy beach and a coastal town as well as a large group of people
South Beach which includes a luxury hotel or resort, swimming and a beach
Key West Butterfly and Nature Conservatory featuring signage

Popular places to visit

Southernmost Point

Southernmost Point

4/5(160 reviews)

Snap a memorable photograph from the edge of North America at this monumental landmark.

Southernmost Point
South Beach

South Beach

4/5(52 reviews)

The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

South Beach
Key West Butterfly and Nature Conservatory featuring zoo animals, animals and food

Key West Butterfly and Nature Conservatory

4.5/5(19 reviews)

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

Key West Butterfly and Nature Conservatory

Things to do

Florida: Key West Overseas Highway Self-Driving Tour

Florida: Key West Overseas Highway App-Based Driving Audio Tour

CA $24
per traveller
76% of travellers recommend
Florida: Key West Overseas Highway App-Based Driving Audio Tour
Bahama Village Walking Tour

Bahama Village Walking Tour

CA $43
per adult
Bahama Village Walking Tour
Key West’s Old Town Treasures: A Self-Guided Audio Tour

Key West’s Old Town Treasures: A Self-Guided Audio Tour

CA $22
per adult
Key West’s Old Town Treasures: A Self-Guided Audio Tour
Southernmost Point in the Continental USA!

PRIVATE Welcome to Key West Walking Tour

CA $396
per adult
PRIVATE Welcome to Key West Walking Tour
Key West History And Culture Walking Tour

Southernmost Key West History and Culture Small-Group Walking Tour

CA $58
per adult
Southernmost Key West History and Culture Small-Group Walking Tour
An Audio Guide of Key West’s Journey From Village to Micro State

An Audio Guide of Key West’s Journey From Village to Micro State

CA $17
per adult
An Audio Guide of Key West’s Journey From Village to Micro State
See all activities in Key West

Uptown - Upper Duval Hotel Deals

Southernmost Beach Resort
Southernmost Beach Resort
4 out of 5
1319 Duval Street, Key West, FL
The price is CA $506 per night from May 11 to May 12
CA $506
CA $665 total
includes taxes & fees
May 11 - May 12
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,382 reviews)
"Great to have small beach & pool access! The location is so walkable to all the restaurants. The room had everything we needed - the service cleaning the room was not ideal (seemed like something was always missing… face cloths, the bed comforters, the door unlocked) and the pools weren’t kept as ..."

Reviewed on Apr. 7, 2025

Southernmost Beach Resort
The Reach Key West, Curio Collection by Hilton
The Reach Key West, Curio Collection by Hilton
4 out of 5
1435 Simonton Street, Key West, FL
The price is CA $514 per night from May 5 to May 6
CA $514
CA $663 total
includes taxes & fees
May 5 - May 6
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (923 reviews)
"The main reason we stayed was the beach access. Overall though it was super expensive."

Reviewed on Apr. 8, 2025

The Reach Key West, Curio Collection by Hilton
The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
The price is CA $295 per night from Apr. 13 to Apr. 14
CA $295
CA $395 total
includes taxes & fees
Apr 13 - Apr 14
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8/10 Very Good! (992 reviews)
"Liked the location and walkability."

Reviewed on Apr. 7, 2025

The Southernmost Inn - Adults Only
Southwinds Motel
Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL
The price is CA $299 per night from May 6 to May 7
CA $299
CA $377 total
includes taxes & fees
May 6 - May 7
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,095 reviews)
Great place to stay!
"Very clean and very convenient to get to the beach and Duvall. Perfect location. We'll definitely stay again!"

Reviewed on Apr. 9, 2025

Southwinds Motel
Douglas House
Douglas House
3 out of 5
419 Amelia St, Key West, FL
The price is CA $285 per night from Apr. 20 to Apr. 21
CA $285
CA $332 total
includes taxes & fees
Apr 20 - Apr 21
Stay at this 3-star guesthouse in Key West. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Duval Street and Ernest Hemingway Home ...
9.4/10 Exceptional! (59 reviews)
"Our stay was good, not great. We stayed in room 1 which was in the main level and we could hear the people above us walking in the room. It was very loud and the guests were smokers and going in and out on the porch so many times a day it was crazy. Also on two separate occasions I got decaf coffee ..."

Reviewed on Apr. 10, 2025

Douglas House
Orchid Key Inn - Adults Only
Orchid Key Inn - Adults Only
3.5 out of 5
1004 Duval St, Key West, FL
The price is CA $512 per night from Apr. 16 to Apr. 17
CA $512
CA $576 total
includes taxes & fees
Apr 16 - Apr 17
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
9.8/10 Exceptional! (1,000 reviews)
"Location is great! Our stay was perfect!"

Reviewed on Apr. 2, 2025

Orchid Key Inn - Adults Only
See all 2,861 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

Key West Historic District

Old Town Key West

3.5/5(8 area reviews)

Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.

Old Town Key West
Key West featuring a marina, a coastal town and general coastal views

Downtown Key West

If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Downtown Key West
Harry S. Truman Little White House which includes a house and cycling

Bahama Village

Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
Clarence S. Higgs Memorial Beach Park which includes landscape views, tropical scenes and a sandy beach

Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
Audubon House and Tropical Gardens featuring a house

Key West Historic District

4.5/5(156 area reviews)

Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.

Key West Historic District
Great location for great pictures, very nice beach

White Street Gallery District

When in White Street Gallery District, you can plan a visit to Duval Street and Saint Mary Star of the Sea, some noteworthy sights in the nearby area.

White Street Gallery District

Uptown - Upper Duval

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