Isla Grande Vacation Rentals from CA $106: Short-Term Rentals for 2025

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Vacation Rentals in Isla Grande

"This is where advertisement they told me that display have AC Wi-Fi TV and they don’t have to bring a lot of money for this room and he’s not worth it I wanted to cancel the second night and the lady didn’t want to return my money back I call hotels.com and complained about it and they didn’t do nothing about it and that even cackle back from them I will never book with thing again I don’t mind paying the money if the play is right"

"Very spacious and comfortable home…the best part was the pool and the view! Very safe complex, super attentive and responsive staff (Maria was great!). Everything in the home worked properly and the entire process from booking to checking out was very smooth. Definitely recommend!."

"Muy tranquilo durante la semana. Muy amable en personal"

CA $198 total

includes taxes & fees

Feb 23 - Feb 24

CA $242 total

includes taxes & fees

Feb 23 - Feb 24

CA $805 total

includes taxes & fees

Mar 10 - Mar 11

"All perfect "

Beach nearby, sun loungers, beach towels

"Jim was a superb host and the accommodation is really nice with everything you need for a comfortable stay. The village is simple and friendly and the wildlife great - monkeys and sloths. The lagoon and reef outside the property is really interesting. Will stay again."

"This property was well kept and managed, even with a few glitches the property owners were very responsive. It’s a peaceful environment we wouldn’t hesitate to visit again."

"The property was stunning and the staff was amazing. Every meal prepared by the staff was better than the next. "

CA $842 total

includes taxes & fees

Feb 23 - Feb 24

CA $549 total

includes taxes & fees

Feb 23 - Feb 24

"Rachel (the property owner) is the BEST! The car I rented couldn’t get up the steep driveway and she was there immediately to offer help. The views from the house are spectacular. We spent most of our time outside because there is a nice breeze off the ocean. I can hear howler monkeys. "

"The furnishings are worn. The second bedroom is only suitable for small children. The house is only a few metres from a busy main road with noisy traffic. The beach is unattractive. The water is too shallow for swimming. And the house is NOT in the “historic centre” of Portobelo, which is several kilometres away and consists of the ruins of a fort and a church. We were so disappointed we left after one night."

"If enjoy and appreciate nature this is a wonderful place. You have all the basics necessary for unforgettable stay. The local people are very nice and welcoming. The see is magnificent.! "

"La comunicación con los anfitriones siempre fue buena, siempre atentos, recibíamos respuesta inmediata a cualquier consulta. La atencion muy buena, Chente y Laura estaban atentos a todo lo que se necesitara. Lindas vistas y muy cómodas las cabañas. Recomendado!!"

"Great views and a relaxing time was had at this comfortable sea side duplex. We were the only renters so we had the whole yard and pool to ourselves. Bob was an excellent resident owner host and the support staff of Maria and Ilariao were perfect and there when we needed help. Getting to Michi was an adventure especially at night and at the end of Mardi Gras...the road and the citizens were a challenge. After we got the lay of the land driving the area and meeting the residents of the Portobelo...

CA $690 total

includes taxes & fees

Mar 4 - Mar 5

CA $220 total

includes taxes & fees

Feb 23 - Feb 24

CA $152 total

includes taxes & fees

Feb 28 - Mar 1

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Other types of properties in Isla Grande you may be interested in

CA $1,263 total

includes taxes & fees

Feb 23 - Feb 24

"A very nice place for Panamanian standards. It’s obvious they are in the process of fixing things up but some things still need a little work. The room and beds were very comfortable. The complimentary breakfast and welcome beverage were outstanding. There is a small lagun to swim and snorkel in. Saw lots of small fish but the waves and break made it impossible to go very far. The facility is very isolated from the rest of the island which can be nice but also very isolated. The parking lot has...

"This is where advertisement they told me that display have AC Wi-Fi TV and they don’t have to bring a lot of money for this room and he’s not worth it I wanted to cancel the second night and the lady didn’t want to return my money back I call hotels.com and complained about it and they didn’t do nothing about it and that even cackle back from them I will never book with thing again I don’t mind paying the money if the play is right"

Find out more about Isla Grande

Everything you need to know about Isla Grande vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Isla Grande vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Isla Grande vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Isla Grande vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Isla Grande. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Isla Grande vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Isla Grande vacation rentals we have selected for you start as low as CA $106 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Isla Grande rentals

At Expedia, we put the best Isla Grande vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Isla Grande rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Isla Grande vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Isla Grande. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Recent reviews of Isla Grande properties

5/5 Excellent

"Love this place and would return back numerous times"

A verified traveller stayed at Ciel y Miel

Posted 9 days ago

3/5 Okay

"The idea of "Panama time" was prevalent on property. After traveling all day room was 2 hours behind for being ready, no keys given until requested on 2nd day, dinner offer by owners personal chef not prepared on time (left after waiting too long). BUT the owner constantly tried to make up for many things and that was appreciated. The dock was nice to relax on. The crew took people out for boat rides daily. Biggest problem was the restaurant under new management. Arrogant and lacked cooking skills and most things unavailable on the menu. Until new restaurant management occurs we suggest El Bongo next door. Great food and super ambiance. I do want to thank the owner of the hostel for his efforts having his chef make breakfast for us on the final morning. Of course, the follow through or "Panama time" really messed with our enjoyment. He really tried to please us, just not organized with his time and no strong staff to cover for him. Very nice fella and we wish him the best of luck."

A verified traveller stayed at Villa Bella Portobelo

Posted 10 days ago

5/5 Excellent

"Great place to stay in Portobelo! Lovely terrace to sit out in overlooking the sea. Room very comfortable..Above all, the staff are first class! Manager George was super helpful! All the staff wete great! Also ..the food was wonderful...best breakfast we had in Panama. Definitely would recommend this place to stay! "

A verified traveller stayed at Casa Congo - Rayo Verde - Restaurante

Posted 2 months ago

Casa Anzuelo is an oceanfront home that is all about the water and nature.

5/5 Excellent

Great stay in lovely place

"Jim was a superb host and the accommodation is really nice with everything you need for a comfortable stay. The village is simple and friendly and the wildlife great - monkeys and sloths. The lagoon and reef outside the property is really interesting. Will stay again."

A verified traveller stayed at Casa Anzuelo is an oceanfront home that is all about the water and nature.

Posted 5 months ago

Spacious Beach House on the ocean front with huge pool and patio.

5/5 Excellent

Great host and beautiful property

"Very spacious and comfortable home…the best part was the pool and the view! Very safe complex, super attentive and responsive staff (Maria was great!). Everything in the home worked properly and the entire process from booking to checking out was very smooth. Definitely recommend!."

A verified traveller stayed at Spacious Beach House on the ocean front with huge pool and patio.

Posted 6 months ago

Frequently asked questions

Can I find vacation rentals in Isla Grande?

Yes, we have vacation rentals near top sights in Isla Grande, or you can select a more secluded option if you'd like a relaxing place to stay. Isla Grande is known for its parks.

What are some of the best vacation home rentals in Isla Grande?

Spacious Beach House on the ocean front with huge pool and patio.: Visitors like this Isla Grande vacation home rental. It is located on the beach and has an outdoor pool, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind.

How many vacation rentals will I find in Isla Grande?

With 3 Expedia vacation rentals, you're sure to find just the right place for your Isla Grande stay.

What can I see and do in Isla Grande?

While you're exploring the area, Isla Mamey and Blanca Beach are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Portobelo National Park and San Felipe Church.

What are vacation rentals like in Isla Grande?

Vacation rentals are private properties you can stay in for several days or more in Isla Grande. Vacation rentals offer extras such as laundry facilities and kitchens so you'll have everything you need. If you're concerned about a sanitized environment, vacation rentals can provide a sense of seclusion away from shared hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family gatherings.

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Isla Grande Vacation Rentals

Plan, book, stay with confidence

Check prices for these dates

Vacation Rentals in Isla Grande

Brother Sun Villas

Brother Sun Villas

Spacious Beach House on the ocean front with huge pool and patio.

Spacious Beach House on the ocean front with huge pool and patio.

Piscina Mar en el Paraíso Caribe

Piscina Mar en el Paraíso Caribe

Cabaña La Punta op het Strand!!

Cabaña La Punta op het Strand!!

Alquiler vacacional en Playa Escondida and Marina /Descuento semanal/mensual

Alquiler vacacional en Playa Escondida and Marina /Descuento semanal/mensual

Casa Frente al Mar - Isla Grande

Casa Frente al Mar - Isla Grande

Casa Anzuelo is an oceanfront home that is all about the water and nature.

Casa Anzuelo is an oceanfront home that is all about the water and nature.

Caribbean Beach House with Pool

Caribbean Beach House with Pool

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

Casa Dinis - Casa Grande - Centro DE Portobelo

Casa Dinis - Casa Grande - Centro DE Portobelo

Casa Dinis - Loft - CON Vistas Bahia DE Portobelo

Casa Dinis - Loft - CON Vistas Bahia DE Portobelo

Cara al mar Cacique

Cara al mar Cacique

BEAUTIFUL APARTMENT IN FRONT OF THE SEA

BEAUTIFUL APARTMENT IN FRONT OF THE SEA

Paraiso de Ensueño Caribeño

Paraiso de Ensueño Caribeño

Pebos Reef with amazing terrace over the sea - apartment #1

Pebos Reef with amazing terrace over the sea - apartment #1

A fantastic place between the sea and the jungle

A fantastic place between the sea and the jungle

San Marino Duo, this is casa 36 - Book one or both Casa 36 & 37

San Marino Duo, this is casa 36 - Book one or both Casa 36 & 37

Caribbean Paradise - Beachfront Getaway

Caribbean Paradise - Beachfront Getaway

Nice house in Portobelo, Skybluebyguanche

Nice house in Portobelo, Skybluebyguanche

Despierta sobre el mar

Despierta sobre el mar

Other types of properties in Isla Grande you may be interested in

Ordovician Beach Resort

Ordovician Beach Resort

Coconut Grove Lodge

Coconut Grove Lodge

Brother Sun Villas

Brother Sun Villas

Find out more about Isla Grande

Find out more about Isla Grande

Recent reviews of Isla Grande properties

Recent reviews of Isla Grande properties

Ciel y Miel

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Explore a world of travel with Expedia

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