Isla Grande Vacation Rentals : Short-Term Rentals for 2025

Q: What are some of the best vacation home rentals in Isla Grande?

Brother Sun Villas : Visitors like this Isla Grande vacation home rental. It is located on the beach and has an outdoor pool, a balcony, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop, and a microwave. Kick off your shoes and enjoy yourself with a terrace and a garden.

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Vacation Rentals in Isla Grande

"This is where advertisement they told me that display have AC Wi-Fi TV and they don’t have to bring a lot of money for this room and he’s not worth it I wanted to cancel the second night and the lady didn’t want to return my money back I call hotels.com and complained about it and they didn’t do nothing about it and that even cackle back from them I will never book with thing again I don’t mind paying the money if the play is right"

"Very spacious and comfortable home…the best part was the pool and the view! Very safe complex, super attentive and responsive staff (Maria was great!). Everything in the home worked properly and the entire process from booking to checking out was very smooth. Definitely recommend!."

"Great views and a relaxing time was had at this comfortable sea side duplex. We were the only renters so we had the whole yard and pool to ourselves. Bob was an excellent resident owner host and the support staff of Maria and Ilariao were perfect and there when we needed help. Getting to Michi was an adventure especially at night and at the end of Mardi Gras...the road and the citizens were a challenge. After we got the lay of the land driving the area and meeting the residents of the Portobelo...

"All perfect "

Beach nearby, sun loungers, beach towels

"Jim was a superb host and the accommodation is really nice with everything you need for a comfortable stay. The village is simple and friendly and the wildlife great - monkeys and sloths. The lagoon and reef outside the property is really interesting. Will stay again."

"This property was well kept and managed, even with a few glitches the property owners were very responsive. It’s a peaceful environment we wouldn’t hesitate to visit again."

"If enjoy and appreciate nature this is a wonderful place. You have all the basics necessary for unforgettable stay. The local people are very nice and welcoming. The see is magnificent.! "

"Muy tranquilo durante la semana. Muy amable en personal"

CA $200 total

includes taxes & fees

Jan 29 - Jan 30

CA $222 total

includes taxes & fees

Jan 23 - Jan 24

"The furnishings are worn. The second bedroom is only suitable for small children. The house is only a few metres from a busy main road with noisy traffic. The beach is unattractive. The water is too shallow for swimming. And the house is NOT in the “historic centre” of Portobelo, which is several kilometres away and consists of the ruins of a fort and a church. We were so disappointed we left after one night."

"A beautiful beachfront property with hammocks, snorkeling, kayaks and a lovely staff to prepare meals made this the ideal location for our family Christmas holiday."

"La comunicación con los anfitriones siempre fue buena, siempre atentos, recibíamos respuesta inmediata a cualquier consulta. La atencion muy buena, Chente y Laura estaban atentos a todo lo que se necesitara. Lindas vistas y muy cómodas las cabañas. Recomendado!!"

"Rachel (the property owner) is the BEST! The car I rented couldn’t get up the steep driveway and she was there immediately to offer help. The views from the house are spectacular. We spent most of our time outside because there is a nice breeze off the ocean. I can hear howler monkeys. "

CA $243 total

includes taxes & fees

Jan 23 - Jan 24

CA $154 total

includes taxes & fees

Jan 31 - Feb 1

CA $858 total

includes taxes & fees

Jan 23 - Jan 24

CA $698 total

includes taxes & fees

Jan 23 - Jan 24

On the beach, sun loungers, beach towels

"What a fantastic property! You could not ask for more if you plan to stay on the Caribbean side of Panama... Casa Buenaventura was perfect for our troop of 4 adults and 5 children. Clean, well appointed, lots of space... and Gabriel was the best! He met us personally upon check in to show the house, provide us with a full itinerary for 5 days of fun, beaches, private boat tour, short trips along the coast, snorkeling, and more! Additionally, Gabriel was only a quick What'sApp text away with any...

CA $402 total

includes taxes & fees

Jan 23 - Jan 24

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Other types of properties in Isla Grande you may be interested in

"A very nice place for Panamanian standards. It’s obvious they are in the process of fixing things up but some things still need a little work. The room and beds were very comfortable. The complimentary breakfast and welcome beverage were outstanding. There is a small lagun to swim and snorkel in. Saw lots of small fish but the waves and break made it impossible to go very far. The facility is very isolated from the rest of the island which can be nice but also very isolated. The parking lot has...

"The hotel is in a beautiful setting overlooking the ocean. The pool and deck are great to relax in and watch the waves. The restaurant food was good (need hour notice for dinner). The rooms are really rustic and ours did not have AC. Also, note that there is not a public beach on Isla Grande. We spent all day at Coconuts on the other side of island at their beach and would probably stay there if we went again. We were traveling with 2 teens. "

"This is where advertisement they told me that display have AC Wi-Fi TV and they don’t have to bring a lot of money for this room and he’s not worth it I wanted to cancel the second night and the lady didn’t want to return my money back I call hotels.com and complained about it and they didn’t do nothing about it and that even cackle back from them I will never book with thing again I don’t mind paying the money if the play is right"

Find out more about Isla Grande

Everything you need to know about Isla Grande vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Isla Grande vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Isla Grande vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Isla Grande vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Isla Grande. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Isla Grande vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Isla Grande vacation rentals we have selected for you start as low as per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Isla Grande rentals

At Expedia, we put the best Isla Grande vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Isla Grande rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Isla Grande vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Isla Grande. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Isla Grande?

Yes, we have vacation rentals near top sights in Isla Grande, or you can select a more secluded option if you'd like a relaxing place to stay. Isla Grande is known for its parks.

What are some of the best vacation home rentals in Isla Grande?

Brother Sun Villas: Visitors like this Isla Grande vacation home rental. It is located on the beach and has an outdoor pool, a balcony, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop, and a microwave. Kick off your shoes and enjoy yourself with a terrace and a garden.

How many vacation rentals will I find in Isla Grande?

With 3 Expedia vacation rentals, you're sure to find just the right place for your Isla Grande stay.

What can I see and do in Isla Grande?

While you're exploring the area, Isla Mamey and Blanca Beach are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Playa La Angosta and Portobelo National Park.

What are vacation rentals like in Isla Grande?

Vacation rentals are private properties you can stay in for several days or more in Isla Grande. Vacation rentals offer extras such as laundry facilities and kitchens so you'll have everything you need. If you're concerned about a sanitized environment, vacation rentals can provide a sense of seclusion away from shared hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family gatherings.

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Isla Grande Vacation Rentals

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Vacation Rentals in Isla Grande

Brother Sun Villas

Spacious Beach House on the ocean front with huge pool and patio.

Alquiler vacacional en Playa Escondida and Marina /Descuento semanal/mensual

San Marino Duo, this is casa 36 - Book one or both Casa 36 & 37

Casa Frente al Mar - Isla Grande

Casa Anzuelo is an oceanfront home that is all about the water and nature.

Caribbean Beach House with Pool

Paraiso de Ensueño Caribeño

Piscina Mar en el Paraíso Caribe

Nice house in Portobelo, Skybluebyguanche

BEAUTIFUL APARTMENT IN FRONT OF THE SEA

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

A fantastic place between the sea and the jungle

Cara al mar Cacique

Pebos Reef with amazing terrace over the sea - apartment #1

Cabaña La Punta op het Strand!!

Despierta sobre el mar

Casa Dinis - Casa Grande - Centro DE Portobelo

Caribbean Paradise - Beachfront Getaway

HERMOSA Y COMODA CASA EN LAS COSTAS DEL MAR CARIBE<br><br>IN FRONT OF THE SEA

Other types of properties in Isla Grande you may be interested in

Coconut Grove Lodge

Sister Moon Hotel

Brother Sun Villas

Find out more about Isla Grande

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