Find hotels in Depew, NY from CA $99

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check Depew hotel prices

Tomorrow night
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top 10 Depew hotels and places to stay

La Quinta Inn & Suites by Wyndham Buffalo Amherst
2.5 star property
8.4 out of 10, Very good, (1637)
"The room was comfortable and well-maintained, and the location was super convenient—close to everything we needed. The check-in process was quick and easy, which made the whole experience even better. I'd definitely come back next time I'm in town. "
The price is CA $107
CA $121 total
includes taxes & fees
Nov 25 - Nov 26
La Quinta Inn & Suites by Wyndham Buffalo Amherst
M Hotel Buffalo
3.5 star property
7.0 out of 10, Good, (1090)
"Convenient hotel for shopping. Staff friendly and helpful. Rooms are dated and worn and need attention."
The price is CA $142
CA $162 total
includes taxes & fees
Dec 9 - Dec 10
M Hotel Buffalo
Hampton Inn Buffalo - Amherst, NY
2.5 star property
9.4 out of 10, Exceptional, (1679)
"Clean and professional staff"
The price is CA $137
CA $156 total
includes taxes & fees
Dec 2 - Dec 3
Hampton Inn Buffalo - Amherst, NY
Buffalo Airport Hotel
3.0 star property
8.0 out of 10, Very good, (2175)
"Front desk staff was very kind. The only challenge we had was about our room numbers. 100s and 300s are on the 1st floor, 200s and 400s are on the 2nd floor which was a little confusing! However it was a good experience with this hotel, will come back again."
The price is CA $126
CA $144 total
includes taxes & fees
Dec 4 - Dec 5
Buffalo Airport Hotel
Wyndham Garden Buffalo Downtown
3.0 star property
9.0 out of 10, Wonderful, (1220)
"Great location, clean & friendly"
The price is CA $167
CA $190 total
includes taxes & fees
Nov 25 - Nov 26
Wyndham Garden Buffalo Downtown
Hyatt Regency Buffalo / Hotel and Conference Center
3.5 star property
7.8 out of 10, Good, (1263)
" A"
The price is CA $203
CA $231 total
includes taxes & fees
Dec 2 - Dec 3
Hyatt Regency Buffalo / Hotel and Conference Center
Quality Inn Near Walden Galleria Mall
2.5 star property
8.0 out of 10, Very good, (1003)
"Very convenient. Helpful, friendly staff. :)"
The price is CA $123
CA $140 total
includes taxes & fees
Dec 2 - Dec 3
Quality Inn Near Walden Galleria Mall
Home2 Suites by Hilton Amherst Buffalo
3.0 star property
8.6 out of 10, Excellent, (1006)
"Easy and clean"
The price is CA $166
CA $189 total
includes taxes & fees
Dec 19 - Dec 20
Home2 Suites by Hilton Amherst Buffalo
Garden Place Hotel
3.5 star property
7.8 out of 10, Good, (1557)
"My stay was relaxing. Second time here and its a wonderful experience!!!"
The price is CA $128
CA $146 total
includes taxes & fees
Nov 20 - Nov 21
Garden Place Hotel
Extended Stay America Suites - Buffalo - Airport
2.5 star property
7.6 out of 10, Good, (303)
"Staff was well behaved awesome customer service will definitely book again "
The price is CA $114
CA $130 total
includes taxes & fees
Nov 19 - Nov 20
Extended Stay America Suites - Buffalo - Airport
Sleep Inn & Suites Buffalo Airport
2.5 star property
8.0 out of 10, Very good, (1405)
"Great staff "
The price is CA $104
CA $118 total
includes taxes & fees
Dec 3 - Dec 4
Sleep Inn & Suites Buffalo Airport
La Quinta Inn by Wyndham Buffalo Airport
2.5 star property
7.6 out of 10, Good, (1062)
"It was very perfume smelling, and our room deadbolt didn't work."
The price is CA $115
CA $131 total
includes taxes & fees
Nov 21 - Nov 22
La Quinta Inn by Wyndham Buffalo Airport
Best Western Buffalo Inn & Suites
2.5 star property
8.8 out of 10, Excellent, (443)
"My room key wasn’t properly encoded and didn’t work the first time. However, everything else was terrific! Great breakfast, too!"
The price is CA $135
CA $154 total
includes taxes & fees
Nov 24 - Nov 25
Best Western Buffalo Inn & Suites
Sleep Inn
2.5 star property
8.6 out of 10, Excellent, (1011)
"Excellent "
The price is CA $99
CA $113 total
includes taxes & fees
Dec 3 - Dec 4
Sleep Inn
Hyatt Place Buffalo/Amherst
3.0 star property
9.2 out of 10, Wonderful, (1004)
"Nice place. Good value for money "
The price is CA $168
CA $191 total
includes taxes & fees
Nov 24 - Nov 25
Hyatt Place Buffalo/Amherst
Comfort Inn University
2.5 star property
7.8 out of 10, Good, (1012)
"Quiet, convenient location for shopping and A good price. "
The price is CA $112
CA $127 total
includes taxes & fees
Dec 2 - Dec 3
Comfort Inn University
Hilton Garden Inn Buffalo Downtown
3.0 star property
8.6 out of 10, Excellent, (1005)
"After seeing mixed reviews, I was a little bit nervous for my stay here. I was pleasantly surprised by the hotel and the staff. The hotel is modern, clean and well kept. Our room was ready when we arrived. On the weekend we were able to street park for free which was awesome. We didn’t use the facilities or visit the restaurant so cannot comment on them. But there were nearby bars and coffee shops that we enjoyed which were within a few minute walk. And we were able to both walk to the Arena as...
The price is CA $183
CA $208 total
includes taxes & fees
Nov 25 - Nov 26
Hilton Garden Inn Buffalo Downtown
Holiday Inn Express Cheektowaga North East, an IHG Hotel
2.5 star property
8.0 out of 10, Very good, (1006)
"Overall a good experience. Only thing was the towels smelled musty and the mirror wasn’t clean when we arrived. Otherwise, good location and quiet. "
The price is CA $134
CA $152 total
includes taxes & fees
Nov 20 - Nov 21
Holiday Inn Express Cheektowaga North East, an IHG Hotel
Curtiss Hotel, Ascend Hotel Collection
5.0 star property
9.2 out of 10, Wonderful, (1012)
"Beautiful and extremely huge room! Loved the sitting area with bar. From the lights to temp control, everything was Smart technology. Palatial bathroom w jacuzzi tub. Such luxuries were greatly appreciated! "
The price is CA $265
CA $301 total
includes taxes & fees
Nov 19 - Nov 20
Curtiss Hotel, Ascend Hotel Collection
Holiday Inn Express Hotel & Suites Buffalo-Airport, an IHG Hotel
2.5 star property
8.4 out of 10, Very good, (1005)
"Great place close to airport."
The price is CA $143
CA $162 total
includes taxes & fees
Dec 8 - Dec 9
Holiday Inn Express Hotel & Suites Buffalo-Airport, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Depew
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What's the best place for a stay in Depew?

Located 2.9 mi (4.6 km) from the heart of Depew, M Hotel Buffalo is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Buffalo Airport Hotel and Sleep Inn & Suites Buffalo Airport. See all available top hotels, or vacation rentals in Depew.

What's the top vacation rental in Depew?

Beautiful furnished 2 bdr great location Elmwood: This vacation home rental outside of Depew offers a garden, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Depew.

If I need to cancel my hotel reservation in Depew, will I receive a refund?

Yes! Most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.

Where can I learn more about changing or cancelling my trip to Depew?

For more information about picking new dates or cancelling your trip to Depew, click here.

What's the best budget-friendly hotel in Depew?

Based on our traveler reviews, Pink Fountain Motor Inn is a top choice for a less expensive stay. View all budget hotels in Depew.

What's the best hotel for a couple going to Depew?

Pink Fountain Motor Inn is a favorite property for couples, and features cable TV and free WiFi. See all romantic hotels in Depew.

What are some accommodations with pools in Depew?

M Hotel Buffalo: Hotel, 6-minute walk from Walden Galleria Mall. Features buffet, an indoor pool, and free self parking. Niagara Riverside Resort, BW Premier Collection and Hampton Inn Buffalo - Amherst, NY are a couple of other choices that feature an onsite pool. View all hotels with pools in Depew.

What is the best spa hotel in Depew?

Pink Fountain Motor Inn is a top spa hotel with 14 rooms, free WiFi, and free self parking. Kick back and relax in the spa tub.

What's the best place to stay near Buffalo Niagara International Airport (BUF)?

Days Hotel by Wyndham Buffalo Airport is a popular 3-star hotel featuring free breakfast and a restaurant. It's located a short 0.3 mi (0.5 km) from Buffalo Niagara Intl. Airport. Other places to stay within close proximity to the airport include Hilton Garden Inn Buffalo Airport and Courtyard Buffalo Airport.

What is staying in Depew like?

Visitors can enjoy all that Depew has to offer including the shopping, restaurants, and sporting events. Tourists can also enjoy so much more including its waterfalls. A top sight in the area is KeyBank Center. In Depew, there are 12 hotels and other accommodations to choose from. Find out more about Depew.

What are the top places to visit in Depew?

KeyBank Center is a notable place to visit in the area. You'll also find Holiday Twin Rinks and Walden Galleria Mall in the area. Check out what more to see and do in Expedia's Depew guide.

How should I get around Depew?

To see more of the larger area, ride aboard one of the trains from Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.

What's the weather like in Depew?

The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 29°F. The snowiest months in Depew are January, March, February, and December, with each month seeing an average of 17 inches of snowfall.