Find Hotels by Independent in Defiance from CA $85
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Top Defiance Independent Hotels

The Wildwood Hotel
The Wildwood Hotel
9.0 out of 10, Wonderful, (1538)
The price is CA $126
CA $152 total
includes taxes & fees
Apr 7 - Apr 8

Relax Inn Saint Charles
Relax Inn Saint Charles
6.4 out of 10, (809)
The price is CA $90
CA $103 total
includes taxes & fees
Apr 3 - Apr 4

The Lodge Hotel and Banquets
The Lodge Hotel and Banquets
4.6 out of 10, (305)
The price is CA $85
CA $104 total
includes taxes & fees
Apr 3 - Apr 4

River Sirens Hotel
River Sirens Hotel
10.0 out of 10, Exceptional, (136)
The price is CA $205
CA $234 total
includes taxes & fees
Apr 13 - Apr 14

Economy Inn Wentzville
Economy Inn Wentzville
6.4 out of 10, (409)
The price is CA $100
CA $114 total
includes taxes & fees
Apr 4 - Apr 5

Research Park Inn St Louis West – Chesterfield
Research Park Inn St Louis West – Chesterfield
5.8 out of 10, (1006)

The Inn at Elijah McLeans
The Inn at Elijah McLeans
9.0 out of 10, Wonderful, (107)
The price is CA $185
CA $211 total
includes taxes & fees
Apr 3 - Apr 4

Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
10.0 out of 10, Exceptional, (25)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find out more about Defiance
Find out more about Defiance
Independent Defiance Hotel Guide
Some globe-trotters will stay anywhere that offers a cheap deal, but others prefer to book with their favourite chain. Thanks to Expedia.ca’s range of Independent in Defiance, St. Louis, you no longer have to choose between the two. Known for their comfortable rooms and friendly staff, each of the best Independent Defiance promises a top quality travel experience.
Recent Reviews in Defiance
Recent Reviews in Defiance

Sonesta ES Suites St. Louis - Chesterfield
5/5 Excellent
Great Stay at Exceptional Value
"The Sonesta ES Suites in Chesterfield, MO exceeded our expectations in all areas. We had not stayed in a Sonesta property before this visit, but based on a most pleasant experience we will absolutely use them again if available when traveling in the future. "
A verified traveller stayed at Sonesta ES Suites St. Louis - Chesterfield
Posted 1 day ago
Explore a world of travel with Expedia
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Defiance Hotels by Brand
Hotels near popular St. Louis Attractions
- Hotels near August A. Busch Memorial Conservation Area
- Hotels near Chandler Hill Vineyards
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near Sugar Creek Winery
- Hotels near Yellow Farmhouse Winery
- Hotels near Broemmelsiek Park
- Hotels near Matson Hill Park Trailhead
- Hotels near Hamburg Trail Trailhead
- Hotels near Six Flags St. Louis
- Hotels near Ameristar Casino St. Charles
More Accommodation Types in Defiance
Explore more hotels
- Drury Plaza Hotel St. Louis St. Charles
- Best Western Plus St. Louis West-Westport
- Crowne Plaza St. Louis Airport by IHG
- Drury Plaza Hotel St. Louis Chesterfield
- Holiday Inn St. Louis - Creve Coeur by IHG
- Embassy Suites by Hilton St. Louis St. Charles
- Courtyard by Marriott St Louis Westport Plaza
- Holiday Inn St. Louis West Six Flags by IHG
- Hampton Inn St. Charles St. Peters
- Sleep Inn & Suites O'Fallon MO - Technology Drive
- Country Inn & Suites by Radisson, St. Charles Historic District
- Holiday Inn Express St. Louis West - O'Fallon by IHG
- Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
- Hilton St. Louis Frontenac
- DoubleTree by Hilton Hotel St. Louis - Chesterfield
- Courtyard by Marriott St Louis Creve Coeur
- Drury Inn & Suites Southwest St. Louis
- Relax Inn Saint Charles
- Comfort Suites St Charles - St Louis
- Comfort Inn St Louis – Airport
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