Find Hotels by Independent in Defiance from CA $82
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Top Defiance Independent Hotels

The Wildwood Hotel
The Wildwood Hotel
9.0 out of 10, Wonderful, (1481)
The price is CA $130
CA $157 total
includes taxes & fees
May 6 - May 7

Relax Inn Saint Charles
Relax Inn Saint Charles
6.4 out of 10, (834)
The price is CA $87
CA $100 total
includes taxes & fees
Apr 28 - Apr 29

The Lodge Hotel and Banquets
The Lodge Hotel and Banquets
4.8 out of 10, (315)
The price is CA $87
CA $106 total
includes taxes & fees
Apr 27 - Apr 28

River Sirens Hotel
River Sirens Hotel
9.8 out of 10, Exceptional, (138)
The price is CA $164
CA $186 total
includes taxes & fees
Apr 27 - Apr 28

Economy Inn Wentzville
Economy Inn Wentzville
6.4 out of 10, (415)
The price is CA $97
CA $110 total
includes taxes & fees
Apr 26 - Apr 27

Research Park Inn St Louis West – Chesterfield
Research Park Inn St Louis West – Chesterfield
5.8 out of 10, (1006)

The Inn at Elijah McLeans
The Inn at Elijah McLeans
9.2 out of 10, Wonderful, (109)
The price is CA $180
CA $205 total
includes taxes & fees
Apr 27 - Apr 28

Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
10.0 out of 10, Exceptional, (27)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find out more about Defiance
Find out more about Defiance
Independent Defiance Hotel Guide
Some globe-trotters will stay anywhere that offers a cheap deal, but others prefer to book with their favourite chain. Thanks to Expedia.ca’s range of Independent in Defiance, St. Louis, you no longer have to choose between the two. Known for their comfortable rooms and friendly staff, each of the best Independent Defiance promises a top quality travel experience.
Recent Reviews in Defiance
Recent Reviews in Defiance

Wingate by Wyndham St. Louis/Fenton Route 66
5/5 Excellent
"Very nice"
A verified traveller from GREENVILLE stayed at Wingate by Wyndham St. Louis/Fenton Route 66
Posted 1 day ago
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Defiance Hotels by Brand
Hotels near popular St. Louis Attractions
- Hotels near Chandler Hill Vineyards
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near August A. Busch Memorial Conservation Area
- Hotels near Sugar Creek Winery
- Hotels near Broemmelsiek Park
- Hotels near Yellow Farmhouse Winery
- Hotels near Six Flags St. Louis
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Ameristar Casino St. Charles
- Hotels near Mississippi River
More Accommodation Types in Defiance
Explore more hotels
- Drury Plaza Hotel St. Louis Chesterfield
- Baymont by Wyndham St. Charles
- Best Western Plus St. Louis West-Westport
- Holiday Inn St. Louis - Creve Coeur by IHG
- Hampton Inn St. Charles St. Peters
- Courtyard by Marriott St Louis Westport Plaza
- Embassy Suites by Hilton St. Louis St. Charles
- Drury Inn & Suites Southwest St. Louis
- Holiday Inn St. Louis West Six Flags by IHG
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Relax Inn Saint Charles
- Country Inn & Suites by Radisson, St. Peters, MO
- Hilton St. Louis Frontenac
- Drury Inn & Suites St. Louis St. Peters
- Courtyard by Marriott St Louis Creve Coeur
- Sleep Inn & Suites O'Fallon MO - Technology Drive
- Country Inn & Suites by Radisson, St. Charles Historic District
- Comfort Suites St Charles - St Louis
- Holiday Inn Express St. Louis West - O'Fallon by IHG
- DoubleTree by Hilton St. Louis - Westport
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