Clayton Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon
    Better together
    Save up to CA $1,096 when you book a flight and hotel together*
    lob hotels icon
    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon
    Rest easy
    Plan, book, and manage your trip all in one place

Your Clayton Vacation

Lock in a Clayton vacation package and prepare to experience all this lively city has to offer. Consider staying in the neighborhood of Soulard, which is good for distilleries and craft breweries, bars and pubs and markets. Fill your spare time with tours of St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis, some of the attractions you just have to see during a trip to Clayton. A couple of clicks is all it takes to put together the perfect Clayton vacation on Expedia.

Top Holiday Package Deals in Clayton

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
per person
Feb. 14 - Feb. 17
found 23 hours ago
Roundtrip non-stop flight included
Rochester (ROC) to St. Louis (STL)
8.2/10 Very Good! (723 reviews)
The lady that checked me in was super polite and personable. I hadn’t seen that in a while checking in, so it was refreshing.

Reviewed on Dec. 13, 2024

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
per person
Feb. 14 - Feb. 17
found 23 hours ago
Roundtrip non-stop flight included
Rochester (ROC) to St. Louis (STL)
9/10 Wonderful! (1,420 reviews)
Awesome place to visit

Reviewed on Dec. 23, 2024

Moonrise Hotel

Moonrise Hotel

4 out of 5
West End
per person
Feb. 14 - Feb. 17
found 23 hours ago
Roundtrip non-stop flight included
Rochester (ROC) to St. Louis (STL)
9/10 Wonderful! (1,606 reviews)
Love this hotel, very nice and helpful! And clean :)

Reviewed on Dec. 11, 2024

The Cheshire

The Cheshire

4 out of 5
per person
Feb. 14 - Feb. 17
found 23 hours ago
Roundtrip non-stop flight included
Rochester (ROC) to St. Louis (STL)
8.4/10 Very Good! (1,004 reviews)
It is a very nice hotel with English theme. Staff is very friendly. The breakfast is great. The restaurant in hotel is amazing. The neighborhood is nice. The only drawback is that the hotel room we stayed needs some maintenance: the fan was very noisy at night, and the bathtub needed some upgrade.

Reviewed on Dec. 25, 2024

The Charles F. Knight Center

The Charles F. Knight Center

2.5 out of 5
per person
Feb. 14 - Feb. 17
found 23 hours ago
Roundtrip non-stop flight included
Rochester (ROC) to St. Louis (STL)
9.4/10 Exceptional! (218 reviews)
We really enjoyed our stay there .. the room was very specious and the staff was very friendly and welcoming

Reviewed on Nov. 19, 2024

Where to stay in Clayton

Find the best Clayton areas and neighborhoods for the activities you enjoy most. Learn more about Clayton
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

3 out of top 10 points of interest in this area
4/5(42 area reviews)

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch National Park or Kiener Plaza might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Find hotel + flight trips in Downtown St. Louis

Clayton Hotel Deals

Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is CA $143 per night from Jan. 12 to Jan. 13
CA $143
CA $167 total
includes taxes & fees
Jan 12 - Jan 13, 2025
8.8/10 Excellent! (2,917 reviews)
Heck of a value!
"Great location for fine dining and to major company headquarters in downtown Clayton. The price is very reasonable for the breakfast alone. Made to order omelettes in a sit-down restaurant, included! Hash browns were perfect. I was in room 206, close to the exits and elevators and I never heard any ..."

Reviewed on Dec. 24, 2024

Clayton Plaza Hotel & Extended Stay
Le Méridien St. Louis Clayton
Le Méridien St. Louis Clayton
4 out of 5
7730 Bonhomme Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is CA $228 per night from Dec. 28 to Dec. 29
CA $228
CA $268 total
includes taxes & fees
Dec 28 - Dec 29
8.6/10 Excellent! (546 reviews)
"Clean, very friendly staff. Very nice rooms!"

Reviewed on Dec. 15, 2024

Le Méridien St. Louis Clayton
The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
5 out of 5
100 Carondelet Plaza, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is CA $774 per night from Jan. 11 to Jan. 12
CA $774
CA $901 total
includes taxes & fees
Jan 11 - Jan 12, 2025
9.2/10 Wonderful! (521 reviews)
"We like everything. This was our first trip to St Louis. The hotel and surroundings exceeded all our expectations. We booked 3 rooms and they got us all on the same floor. It was Christmas and the decorations and festivities were wonderful."

Reviewed on Dec. 10, 2024

The Ritz-Carlton, St. Louis
See all 1,905 properties in Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Frequently asked questions

How much does a Clayton vacation package cost?
From as little as CA $821, you can tailor make your Clayton vacation package. Simply combine hotels, flights and rental cars and be rewarded with discounts.
How do I get a cheap travel package to Clayton?
By bundling. Flights, hotels and rental cars — combine whatever you need into a Clayton vacation package to save a pile of cash. Score even more discounts when you include extras such as tours or experiences to your booking. But that’s not the only good part. You have the freedom to customize your trip your own way. We offer over 550 air carriers and 1,000,000 properties across the globe, so that everyone has a chance to travel and fulfill those vacation dreams.
Where should I stay in Clayton?
With so much to discover in Clayton, it’d be convenient for you to secure a room in a hotel close to its attractions. St. Louis Zoo, Washington University in St. Louis and Forest Park are some good ones to put on your must-see list.
What are the top hotels in Clayton?
If it’s your first time staying in Clayton, secure a room at King Bed, Comfy Environment, Cozy Space or Homewood Suites by Hilton St Louis - Galleria. Both hotels offer friendly service and are top options with many savvy travelers.
How far in advance should I book my Clayton vacation?
It’s difficult to pick the ideal time for airfares, but we usually say the earlier, the better. Most international flights on Expedia become available to compare up to 12 months in advance. If you’re unable to do so, don’t despair. Low prices appear from time to time just weeks before departure dates.
What does an Expedia Clayton travel package include?
With Expedia, you can select any combination of flights, hotels and car rentals to build your perfect Clayton package. Once you’ve made your booking, you can add on the fun things like sightseeing tours and activities. Remember, the more you bundle, the more dollars you’ll save!
What should I know before booking a Clayton travel package?
Whether it’s relaxation or adventure you’re seeking, a Clayton vacation package lets you organize your escape your way. Plus, you’ll get access to great discounts when you combine your hotel with your flights and rental car. The more you bundle, the more you’ll save!
Can I choose my airline with a Clayton Expedia vacation package?
You sure can. We have more than 550 partner airlines worldwide, so fly with the carrier that’s a good fit for your needs.
If I'm not able to travel, can I cancel my Clayton vacation package?
We get that the universe can throw the odd curveball. If you’ve booked a Clayton vacation package and need to amend or cancel it, we can help. We suggest looking up our Customer Service Portal first for information. But generally, if you’ve booked your package in the last 24 hours, you may be able to amend or cancel your itinerary for free. If it’s been more than 24 hours, your hotel, airline or car rental company may charge a fee.

Discover the most popular places to visit in Clayton

Gateway Arch featuring modern architecture, a city and a skyscraper

Gateway Arch

4.5/5(37 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
St. Louis Zoo

St. Louis Zoo

4.5/5(7 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo
Busch Stadium

Busch Stadium

5/5(19 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Busch Stadium

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis: Gateway Ghouls and Hauntings Walking Tour

CA $46
per adult
St. Louis: Gateway Ghouls and Hauntings Walking Tour
Private and Group training for all level of skills

Bullets & BBQ at Indoor Shooting Range in St. Louis County

CA $250
per adult
Bullets & BBQ at Indoor Shooting Range in St. Louis County
St Louis Self-Guided Driving and Walking Audio Tour

St Louis Self-Guided Driving and Walking Audio Tour

CA $22
per traveller
St Louis Self-Guided Driving and Walking Audio Tour
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.