Find hotels in Center, MO from CA $80

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Top 10 Center hotels and places to stay

Lighthouse Hospitality Hannibal

2.5 star property
9.2 out of 10, Wonderful, (102)
"Cute place just off Main Street in Hannibal! I would highly recommend staying here!"
The price is CA $201
CA $280 total
includes taxes & fees
Jan 27 - Jan 28
Lighthouse Hospitality Hannibal

Best Western On The River

2.5 star property
8.6 out of 10, Excellent, (1003)
"Well worn hotel, but for age and location it served us well. Friendly staff."
The price is CA $145
CA $166 total
includes taxes & fees
Jan 29 - Jan 30
Best Western On The River

Garden House Bed and Breakfast

2.0 star property
8.4 out of 10, Very good, (14)
"Very cool Victorian home. Very clean and comfortable with very friendly staff. "
The price is CA $145
CA $167 total
includes taxes & fees
Feb 12 - Feb 13
Garden House Bed and Breakfast

Lighthouse Inn & Suites

4.0 star property
8.8 out of 10, Excellent, (9)
"It was a very nice room. "
The price is CA $202
CA $276 total
includes taxes & fees
Jan 24 - Jan 25
Lighthouse Inn & Suites

Motel 6 Hannibal, MO

2.0 star property
7.4 out of 10, Good, (1000)
"Clean"
The price is CA $80
CA $92 total
includes taxes & fees
Jan 26 - Jan 27
Motel 6 Hannibal, MO

Super 8 by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (1000)
"We arrived late, but the room was clean and the mattress good."
The price is CA $90
CA $104 total
includes taxes & fees
Jan 29 - Jan 30
Super 8 by Wyndham Hannibal

Comfort Inn & Suites - Hannibal

2.5 star property
7.6 out of 10, Good, (539)
"Nice place for a one nights stay"
The price is CA $127
CA $150 total
includes taxes & fees
Jan 29 - Jan 30
Comfort Inn & Suites - Hannibal

Baymont by Wyndham Hannibal

2.5 star property
6.2 out of 10, (609)
"The motel was conveniently located. There were many restuarants nearby. The room was large and the bed was comfortable. The bathromm had the appearance of being a little rundown."
The price is CA $86
CA $99 total
includes taxes & fees
Jan 29 - Jan 30
Baymont by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (134)
"Good quiet"
The price is CA $100
CA $115 total
includes taxes & fees
Jan 25 - Jan 26
Days Inn by Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2.0 star property
7.0 out of 10, Good, (101)
"The heater in the room we were first assigned could not be regulated and the room was too hot. We were moved to another room which was better, but a mouse ran over the cabinet while we were watching TV. It left again through the gap under the entry door, which we then blocked off with a towel. A bit unsettling."
The price is CA $81
CA $93 total
includes taxes & fees
Feb 1 - Feb 2
Howard Johnson BY Wyndham Hannibal

Quality Inn & Suites Hannibal

2.5 star property
7.8 out of 10, Good, (1001)
"Everything but the bathroom in our room was great. I notified the front desk that the toilet was dirty and had dried urine around the base. We have stayed at this hotel several times and this was the only time I remember having an issue with cleanliness. "
The price is CA $133
CA $153 total
includes taxes & fees
Feb 16 - Feb 17
Quality Inn & Suites Hannibal

Sleep Inn & Suites

2.5 star property
9.6 out of 10, Exceptional, (1000)
"We’ve stayed in this hotel 4 times and each time is great. Theres a really nice restaurant next door too."
The price is CA $166
CA $191 total
includes taxes & fees
Feb 9 - Feb 10
Sleep Inn & Suites

The Junction Inn

2.0 star property
5.8 out of 10, (16)
"Good price"
The price is CA $106
CA $112 total
includes taxes & fees
Jan 24 - Jan 25
The Junction Inn

Cannon Dam Cabins

3.0 star property
10.0 out of 10, Exceptional, (1)
"There was a nice outdoor space with a picnic table and fire pit."
The price is CA $108
CA $115 total
includes taxes & fees
Jan 27 - Jan 28
Cannon Dam Cabins

Kennedys Red Barn Inn

2.5 star property
9.2 out of 10, Wonderful, (26)
"Jack and Becky are warm and welcoming. The barn is close to many attractions near the lake. Guests live downstairs and the owners upstairs. The breakfast and cat are great. The room and the whole barn are all wood, very stylish and interesting for city people like me. There is also an interesting heart-shape bathtub without the above-head showing faucet."
The price is CA $117
CA $124 total
includes taxes & fees
Feb 23 - Feb 24
Kennedys Red Barn Inn

FairBridge Inn Express, Monroe City

2.0 star property
9.0 out of 10, Wonderful, (359)
"Great stay."
The price is CA $143
CA $155 total
includes taxes & fees
Jan 24 - Jan 25
FairBridge Inn Express, Monroe City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Center
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

Where is the best place for a stay in Center?

Sleep Inn & Suites, located 14.9 mi (24 km) from the heart of Center, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Best Western On The River and Quality Inn & Suites Hannibal. See all available top hotels, or vacation rentals in Center.

What are some of the best vacation home rentals that Center has to offer?

Peaceful, Country Cottage with Open Floor Plan: This vacation home rental outside of Center is located in a rural location and has a patio, a selection of games, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in Center.

If I need to cancel my hotel reservation in Center, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Center.

Where can I learn more about changing or cancelling my trip to Center?

For more information about updating your trip to Center or cancelling it, go to https://www.expedia.com/service/.

What are some accommodations with pools in Center?

Quality Inn & Suites Hannibal: Features a snack bar, an indoor pool, and free buffet breakfast. Best Western On The River and Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel are a couple of other choices that feature an onsite pool. View all hotels with pools in Center.

What is staying in Center like?

Travelers to Center will find plenty to explore and enjoy. In Center, there are 2 hotels and other accommodations to choose from. Find out more about Center.

What are the top places to visit in Center?

A favorite place to visit is Mark Twain Lake. You'll also find Mark Twain Birthplace State Historic Site and Mark Twain State Park in the area. Check out what more to see and do in Expedia's Center guide.

What's the weather like in Center?

The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 35°F. Average annual precipitation for Center is 47 inches.