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Find Spa Hotels in Cape Girardeau, MO from CA $79

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Top Cape Girardeau Spa Hotels

Hampton Inn Cape Girardeau I 55 East
Courtyard

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (683)
"Always a nice stay"
The price is CA $158
CA $178 total
includes taxes & fees
Jan 12 - Jan 13, 2025
Hampton Inn Cape Girardeau I 55 East
Pear Tree Inn Cape Girardeau West
Lobby

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1000)
"Great for a quick stay on a road trip "
The price is CA $92
CA $103 total
includes taxes & fees
Dec 30 - Dec 31
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Cape Girardeau
Business centre

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (845)
"Wonderful hotel, clean & comfy. Wonderful kickback food and drinks and fabulous breakfast. Amazing value "
The price is CA $129
CA $146 total
includes taxes & fees
Jan 10 - Jan 11, 2025
Drury Inn & Suites Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1000)
"Really good. My kiddo had a tonsillectomy done at the hospital there and the staff were very helpful. Got us extra yogurts so she could eat etc…. Thank you! "
The price is CA $142
CA $160 total
includes taxes & fees
Dec 30 - Dec 31
Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

2.5 star property
9.4 out of 10, Exceptional, (1000)
"Staff was amazing and the suite was very nice and it felt homey."
The price is CA $142
CA $161 total
includes taxes & fees
Jan 12 - Jan 13, 2025
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Candlewood Suites Cape Girardeau, an IHG Hotel
Exterior

Candlewood Suites Cape Girardeau, an IHG Hotel

2.5 star property
8.2 out of 10, Very good, (708)
"Very spacious room with very comfortable bed."
The price is CA $95
CA $115 total
includes taxes & fees
Jan 5 - Jan 6, 2025
Candlewood Suites Cape Girardeau, an IHG Hotel
Pear Tree Inn Cape Girardeau Near the Medical Center
Seasonal outdoor pool

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1003)
"clean room. barking dog"
The price is CA $84
CA $95 total
includes taxes & fees
Dec 30 - Dec 31
Pear Tree Inn Cape Girardeau Near the Medical Center
Town House Inn Cape Giradreau
Desk, free WiFi

Town House Inn Cape Giradreau

2.5 star property
6.0 out of 10, (159)
"It was a room to lay my head at night. Shower didn't work, ceiling paint was peeling and heavy smell of marijuana even though it was a no smoking room!"
The price is CA $79
CA $92 total
includes taxes & fees
Jan 7 - Jan 8, 2025
Town House Inn Cape Giradreau
3+ acre Home with New Hot Tub: Pool Table, Putt-Putt, 4 miles to Downtown
Exterior

3+ acre Home with New Hot Tub: Pool Table, Putt-Putt, 4 miles to Downtown

9.0 out of 10, Wonderful, (26)
"Amazing property that we simply didn't stay long enough to enjoy in its completeness. Billiards and Putt-Putt on entry, so attractive that we started playing before we even unpacked! I'm very artsy interior, and lots of room and outdoor fire pit, multiple decks, and an in-ground pool. The home is even on the grounds, an event venue. Probably a wonderful combination for them! Would enjoy returning, but for a longer stay will you could enjoy all with the property had to offer! Highly recommend it"
The price is CA $395
CA $550 total
includes taxes & fees
Jan 7 - Jan 8, 2025
3+ acre Home with New Hot Tub: Pool Table, Putt-Putt, 4 miles to Downtown
Serenity South -- Gardens, River-Views, and Refreshing Space
Fridge, microwave, oven, stovetop

Serenity South -- Gardens, River-Views, and Refreshing Space

10.0 out of 10, Exceptional, (124)
"This was the second year in a row that we have stayed here. This is a beautiful home to stay in. I love the charm and detail of the house. We stay here after a Christmas party and walk downtown so it’s definitely located in a convenient spot. I will be booking again for next year Great communication with Jo and if there’s any questions I need, Jo is very quick to respond. Thank you for making our stay good!"
The price is CA $215
CA $350 total
includes taxes & fees
Jan 7 - Jan 8, 2025
Serenity South -- Gardens, River-Views, and Refreshing Space
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Cape Girardeau?
Treat yourself to some pampering and book a hotel with a spa. Travelers recommend the gourmet restaurants in Cape Girardeau. Enjoy the historical sites and riverfront during your vacation. Hotels with spas are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel is a top spa hotel featuring a pool and a fitness center.
How many spa hotels will I find in Cape Girardeau?
Among Expedia’s 49 accommodation options in Cape Girardeau, there is 1 spa hotel.
What's there to see and do in Cape Girardeau?
Experience all that Cape Girardeau has to offer when you visit Riverfront Park, eDen Spa & Salon, and Isle Casino Cape Girardeau. If you have a bit of extra time while you’re in the area, you might want to check out Riverfront Bridge Park and Show Me Center.
What is a Cape Girardeau spa hotel?
Spa hotels in Cape Girardeau have full on-site spas offering services such as massages and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.