Photo by Michael Schuier

Find Ladys Island 5 Star Hotels & Resorts from CA $189/night

  • Plan, book, stay with confidence
  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Top Ladys Island 5 Star Hotels

Montage Palmetto Bluff
5.0 star property
9.6 out of 10, Exceptional, (206)
"Montage Palmetto Bluff is a beautiful escape. The entire property is meticulously cared for with wildlife around the area. We saw many deer, fishes, and even some gators in May river. We had a cottage with river views and it was so relaxing. The entire property is dog friendly and I had my two dogs treated like royalty. The River house restaurant is an absolute must. It’s incredibly delicious - so good we ate there twice. My husband and I are already making plans to go back! "
The price is CA $587
CA $745 total
includes taxes & fees
Dec 18 - Dec 19
Montage Palmetto Bluff
Anchorage 1770
5.0 star property
9.2 out of 10, Wonderful, (198)
"What a wonderful place to stay! Room was beautiful. Bed super comfy. Owners were lovely! So friendly!!! Loved the cookies at turn down. Morning breakfast was delish. Rooftop and porch were lovely and relaxing. Loved the view of the marina, water and sunset. Downtown Beaufort was one block away. Can’t say enough positive things!!!"
The price is CA $519
CA $576 total
includes taxes & fees
Nov 27 - Nov 28
Anchorage 1770
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Ladys Island.
Still don't see what you're looking for?
See all properties in Ladys Island.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in Ladys Island?
Experience world-class amenities and impeccable service at Anchorage 1770. Located around the Beaufort neighborhood of Ladys Island, this 5-star hotel is a leading choice based on reviews by Expedia’s customers.
How much does it cost to stay in a 5-star hotel in Ladys Island?
You can find a range of pricing options for 5-star hotels in Ladys Island on Expedia. The amount you pay will depend on your vacation dates, length of your trip and other factors. Compare available properties for your preferred dates and use our pricing and other filters to score the perfect high-end stay.

  • Search for the lowest price per night from CA $189

What makes a hotel 5 stars in Ladys Island?
Impeccable guest service is the hallmark of every 5-star hotel in Ladys Island. From the minute you step through the door, staff attend to your every whim, whether offering luggage assistance and storage or providing in-room massages. Also, hotels must offer upscale amenities to be eligible for a 5-star rating. These can include luxury baths, saunas or spas, swimming pools, gastronomic kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Ladys Island?
Find an indulgent stay that includes your lodging, food, activities and entertainment in Ladys Island with our filter tool. Search for resorts with a 5-star rating and click on the “All inclusive” filter. Be sure to check what’s included in the upfront price. That way, you’re ready to take advantage of the many perks on offer from the moment you arrive.
What are the top 5-star spa hotels in Ladys Island?
Among the leading spa accommodations around Ladys Island, Anchorage 1770 will help you leave behind the worries of everyday life. Select this 5-star option and enjoy a variety of activities and experiences that are designed to enhance your well-being and relaxation.
Are there any 5-star vacation rentals in Ladys Island?
Although there aren’t any 5-star vacation rentals in Ladys Island on our site, we have a range of escapes that promise a fantastic getaway. Find one that matches your needs by searching our vacation rentals in Ladys Island.