4 Stars Hotels in Uptown, Collinsville from CA $126
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Top Uptown 4 Star Hotels

Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
8.4 out of 10, Very good, (3765)
The price is CA $150
CA $177 total
includes taxes & fees
Apr 18 - Apr 19

Moonrise Hotel
Moonrise Hotel
9.0 out of 10, Wonderful, (1761)
The price is CA $213
CA $253 total
includes taxes & fees
Apr 6 - Apr 7

River City Casino & Hotel
River City Casino & Hotel
9.0 out of 10, Wonderful, (1214)
The price is CA $126
CA $167 total
includes taxes & fees
Apr 6 - Apr 7

21C Museum Hotel St Louis
21C Museum Hotel St Louis
9.0 out of 10, Wonderful, (1038)
The price is CA $230
CA $276 total
includes taxes & fees
Apr 17 - Apr 18

Live by Loews - St.Louis
Live by Loews - St.Louis
9.2 out of 10, Wonderful, (1071)
The price is CA $227
CA $270 total
includes taxes & fees
Apr 6 - Apr 7

Le Méridien St. Louis Clayton
Le Méridien St. Louis Clayton
8.8 out of 10, Excellent, (581)
The price is CA $227
CA $267 total
includes taxes & fees
Apr 17 - Apr 18

The Last Hotel
The Last Hotel
7.8 out of 10, Good, (1236)

Embassy Suites by Hilton St. Louis Downtown
Embassy Suites by Hilton St. Louis Downtown
8.6 out of 10, Excellent, (1204)
The price is CA $144
CA $171 total
includes taxes & fees
Apr 20 - Apr 21
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Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Uptown.

Four Seasons Hotel St Louis
999 North Second Street, St. Louis, MO
The price is CA $601 per night from Apr. 4 to Apr. 5
CA $601
CA $703 total
includes taxes & fees
Apr 4 - Apr 5
9.4/10 Exceptional! (995 reviews)
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Recent Reviews in Uptown
Recent Reviews in Uptown

Moonrise Hotel
5/5 Excellent
"Scott was very friendly and professional during the check-in process. The Moonrise is my go-to hotel when I'm in the city for shows."
A verified traveller stayed at Moonrise Hotel
Posted 17 hours ago
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Uptown Hotels by Star Rating
Hotels near Popular Uptown Attractions
- Hotels near World's Largest Catsup Bottle
- Hotels near Kruta Bakery
- Hotels near Mutts on Main Dog Park
- Hotels near Enterprise Center
- Hotels near St. Louis Union Station
- Hotels near Busch Stadium
- Hotels near Gateway Arch
- Hotels near St. Louis Zoo
- Hotels near Washington University in St. Louis
- Hotels near Forest Park
- Hotels near City Museum
- Hotels near Barnes Jewish Hospital
- Hotels near St. Louis University
- Hotels near Dome at America’s Center
- Hotels near America's Center Convention Complex
- Hotels near Fox Theater
- Hotels near Mississippi River
- Hotels near Horseshoe St. Louis Casino
- Hotels near Anheuser-Busch Brewery
- Hotels near St. Louis Aquarium at Union Station
Explore more hotels
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Embassy Suites by Hilton St. Louis Downtown
- Casino Queen Hotel
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Hilton St. Louis at the Ballpark
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- The Cheshire
- The West End
- Forest Park Hotel by MDR
- The Last Hotel
- Angad Arts Hotel
- Hilton Pennywell St. Louis at the Arch
- Marriott St. Louis Grand
- Holiday Inn St. Louis - Downtown Conv Ctr by IHG
- The Royal Sonesta Chase Park Plaza St. Louis
- The Westin St. Louis
- DoubleTree by Hilton St. Louis Forest Park
- The Ritz-Carlton, St. Louis
- Four Seasons Hotel St Louis
- The Knight Center at Washington University