4 Stars Hotels in Otay Mesa, San Diego from CA $142

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Check availability on Otay Mesa 4 Star Hotels

Tonight
Mar 29 - Mar 30
Tomorrow
Mar 30 - Mar 31
Next weekend
Apr 4 - Apr 6
In two weeks
Apr 11 - Apr 13

Top Otay Mesa 4 Star Hotels

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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Otay Mesa.
Pendry San Diego

Pendry San Diego

550 J Street, San Diego, CA
The price is CA $394 per night from Apr. 12 to Apr. 13
CA $394
CA $517 total
includes taxes & fees
Apr 12 - Apr 13
9.2/10 Wonderful! (1,006 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Otay Mesa?
To book a 4-star hotel in Otay Mesa that fits your budget, take advantage of Expedia’s handy filters. Browse the availability during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most economical stay first.

  • Search for the lowest price from CA $364

What's the difference between 5-star and 4-star hotels in Otay Mesa?
Treat yourself to refined living during your Otay Mesa escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are usually filled with amenities, including large beds, complimentary bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more lavish and memorable one. Concierge assistance, elegant décor and world-class dining are a few of the exclusive conveniences and services you’ll likely be able to enjoy.
Does Otay Mesa have any 4-star all-inclusive resorts?
Finding your dream hotel in Otay Mesa is as easy as entering your travel dates and destination, and selecting our “All inclusive” filter. Stay and play where everything is already taken care of like your room, meals and activities, or choose a standard 4-star resort in or around this popular destination.
Are there any 4-star casino hotels in Otay Mesa?
Use our handy filters to refine your Otay Mesa search by amenities, star rating and much more. Whether you’re after the full casino resort experience or simply want to give your luck a try while kicking back in 4-star style, you’re sure to find a stay that strikes just the right balance between entertainment and relaxation.