4 Stars Hotels in Otay Mesa, San Diego from CA $137

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Check availability on Otay Mesa 4 Star Hotels

Tonight
Apr 19 - Apr 20
Tomorrow
Apr 20 - Apr 21
Next weekend
Apr 25 - Apr 27
In two weeks
May 2 - May 4

Top Otay Mesa 4 Star Hotels

Wyndham San Diego Bayside
Exterior

Wyndham San Diego Bayside

4.0 star property
8.2 out of 10, Very good, (5678)
"The staff were really loud in the hallways. 9:30 pm is not late however I'm sure there other areas where staff can assemble and party. Same goes for the morning crew"
The price is CA $224
CA $259 total
includes taxes & fees
May 7 - May 8
Wyndham San Diego Bayside
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1012)
"What a beautiful hotel!!! The view is incredible, the hotel is gorgeous, and the staff is top notch! Restaurant and cafe are wonderful as well. We’ll definitely be back! "
The price is CA $298
CA $394 total
includes taxes & fees
May 19 - May 20
Loews Coronado Bay Resort
San Diego Mission Bay Resort
Outdoor pool, open 9:00 AM to 9:00 PM, cabanas (surcharge)

San Diego Mission Bay Resort

4.0 star property
8.2 out of 10, Very good, (1178)
"Nice facility. Would stay there again."
The price is CA $262
CA $357 total
includes taxes & fees
Apr 21 - Apr 22
San Diego Mission Bay Resort
Legacy Resort Hotel & Spa
Lobby

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2864)
"Everything Great, but No WIFI."
The price is CA $234
CA $264 total
includes taxes & fees
Apr 21 - Apr 22
Legacy Resort Hotel & Spa
Sheraton San Diego Resort
View from room

Sheraton San Diego Resort

4.0 star property
8.2 out of 10, Very good, (2607)
"Great views and restaurants "
The price is CA $220
CA $304 total
includes taxes & fees
Apr 21 - Apr 22
Sheraton San Diego Resort
Hard Rock Hotel San Diego
Outdoor pool

Hard Rock Hotel San Diego

4.0 star property
8.8 out of 10, Excellent, (2663)
"Perfect location for a weekend visit to the action in downtown San Diego. The hotel is very nice, the bar is fun and breakfast in the restaurant was delicious."
The price is CA $246
CA $339 total
includes taxes & fees
Apr 21 - Apr 22
Hard Rock Hotel San Diego
Hilton San Diego Mission Valley
Lobby

Hilton San Diego Mission Valley

4.0 star property
8.0 out of 10, Very good, (1593)
"Would stay here again"
The price is CA $173
CA $195 total
includes taxes & fees
Apr 27 - Apr 28
Hilton San Diego Mission Valley
Manchester Grand Hyatt San Diego
Hypo-allergenic bedding, in-room safe, desk, iron/ironing board

Manchester Grand Hyatt San Diego

4.0 star property
9.0 out of 10, Wonderful, (2767)
"Beautiful property and helpful staff"
The price is CA $262
CA $361 total
includes taxes & fees
Apr 21 - Apr 22
Manchester Grand Hyatt San Diego
Lafayette Hotel & Club
Outdoor pool, open 7:00 AM to 9:00 PM, cabanas (surcharge)

Lafayette Hotel & Club

4.0 star property
9.2 out of 10, Wonderful, (760)
"Just the most fun as a stay I'm San Diego! Great rrstaursnts/bar/pool/gym and staff hospitality. Love thon place!"
The price is CA $313
CA $352 total
includes taxes & fees
Apr 21 - Apr 22
Lafayette Hotel & Club
The Little Italy Hotel Downtown San Diego
Designer store

The Little Italy Hotel Downtown San Diego

4.0 star property
7.8 out of 10, Good, (1007)
"The staff"
The price is CA $155
CA $174 total
includes taxes & fees
Apr 27 - Apr 28
The Little Italy Hotel Downtown San Diego
Omni San Diego Hotel
Lobby sitting area

Omni San Diego Hotel

4.0 star property
9.2 out of 10, Wonderful, (1930)
"Clean, safe, great location!"
The price is CA $321
CA $422 total
includes taxes & fees
Apr 27 - Apr 28
Omni San Diego Hotel
San Diego Marriott Gaslamp Quarter
Exterior

San Diego Marriott Gaslamp Quarter

4.0 star property
8.6 out of 10, Excellent, (1394)
"We visited on a short trip with my 4 kids and this was the easiest trip for us. Loved this location! "
The price is CA $248
CA $279 total
includes taxes & fees
Apr 21 - Apr 22
San Diego Marriott Gaslamp Quarter
Marriott Marquis San Diego Marina
2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)

Marriott Marquis San Diego Marina

4.0 star property
9.2 out of 10, Wonderful, (1633)
"Overall nice hotel but quite busy . Waitstaff isnt exactly the friendliest. Twenty three bucks for grilled cheese and soup bit silly. But one of the best steaks I ever had. Little bit of mold in the shower was quite disheartening. Fantastic view. "
The price is CA $317
CA $406 total
includes taxes & fees
Apr 27 - Apr 28
Marriott Marquis San Diego Marina
Paradise Point Resort & Spa
Aerial view

Paradise Point Resort & Spa

4.0 star property
8.6 out of 10, Excellent, (2144)
"Most amazing place to stay in San Diego! The property is beautiful, fun for ALL ages. I walked and walked and walked, smiling all day long every day. Every single staff member I encountered was beyond kind."
The price is CA $294
CA $400 total
includes taxes & fees
Apr 27 - Apr 28
Paradise Point Resort & Spa
Palihotel San Diego Gaslamp Quarter
Rooftop terrace

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.6 out of 10, Excellent, (1263)
"Super cute hotel! Clean, quiet, great location and the roof top is stunning! "
The price is CA $137
CA $194 total
includes taxes & fees
Apr 21 - Apr 22
Palihotel San Diego Gaslamp Quarter
Hotel del Coronado, Curio Collection by Hilton
Ice skating

Hotel del Coronado, Curio Collection by Hilton

4.0 star property
7.8 out of 10, Good, (1004)
"Best getaway location in San Diego"
The price is CA $441
CA $567 total
includes taxes & fees
May 10 - May 11
Hotel del Coronado, Curio Collection by Hilton
Hyatt Regency Mission Bay Spa and Marina
3 outdoor pools, cabanas (surcharge), pool umbrellas

Hyatt Regency Mission Bay Spa and Marina

4.0 star property
8.4 out of 10, Very good, (1470)
"Loved it! "
The price is CA $234
CA $331 total
includes taxes & fees
Apr 21 - Apr 22
Hyatt Regency Mission Bay Spa and Marina
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
Terrace/patio

The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott

4.0 star property
9.0 out of 10, Wonderful, (848)
"Enjoyed my stay "
The price is CA $206
CA $233 total
includes taxes & fees
Apr 21 - Apr 22
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
Sheraton Mission Valley San Diego Hotel
Outdoor pool

Sheraton Mission Valley San Diego Hotel

4.0 star property
8.4 out of 10, Very good, (1396)
"Clean and spacious rooms"
The price is CA $176
CA $198 total
includes taxes & fees
Apr 21 - Apr 22
Sheraton Mission Valley San Diego Hotel
San Diego Marriott Mission Valley
Property amenity

San Diego Marriott Mission Valley

4.0 star property
8.6 out of 10, Excellent, (1003)
"Friendly helpful staff!"
The price is CA $211
CA $242 total
includes taxes & fees
May 1 - May 2
San Diego Marriott Mission Valley
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Otay Mesa.
Pendry San Diego

Pendry San Diego

550 J Street, San Diego, CA
The price is CA $436 per night from Apr. 21 to Apr. 22
CA $436
CA $562 total
includes taxes & fees
Apr 21 - Apr 22
9.2/10 Wonderful! (1,012 reviews)
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Frequently asked questions

How much does it cost to stay in a 4-star hotel in Otay Mesa?
To book a 4-star hotel in Otay Mesa that fits your budget, take advantage of Expedia’s handy filters. Browse the availability during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most economical stay first.

  • Search for the lowest price from CA $380

What's the difference between 5-star and 4-star hotels in Otay Mesa?
Treat yourself to refined living during your Otay Mesa escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are usually filled with amenities, including large beds, complimentary bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more lavish and memorable one. Concierge assistance, elegant décor and world-class dining are a few of the exclusive conveniences and services you’ll likely be able to enjoy.
Does Otay Mesa have any 4-star all-inclusive resorts?
Finding your dream hotel in Otay Mesa is as easy as entering your travel dates and destination, and selecting our “All inclusive” filter. Stay and play where everything is already taken care of like your room, meals and activities, or choose a standard 4-star resort in or around this popular destination.
Are there any 4-star casino hotels in Otay Mesa?
Use our handy filters to refine your Otay Mesa search by amenities, star rating and much more. Whether you’re after the full casino resort experience or simply want to give your luck a try while kicking back in 4-star style, you’re sure to find a stay that strikes just the right balance between entertainment and relaxation.